Do not expect to be hailed as a hero when you make your great discovery. More likely you will be a ratbag-maybe failed by your examiners. Your statistics, or your observations, or your literature study, or your something else will be patently deficient. Do not doubt that in our enlightened age the really important advances are and will be rejected more often than acclaimed. Nor should we doubt that in our own professional lifetime we too will repudiate with like pontifical finality the most significant insight ever to reach our desk.