Top 100 Quotes & Sayings by Scott Gottlieb
Explore popular quotes and sayings by an American public servant Scott Gottlieb.
Last updated on November 7, 2024.
When some states introduced mandatory smallpox vaccinations during the epidemic of 1898-1903, Americans resisted by the thousands. The ensuing battles produced medical conventions and case law that altered the balance between government authority and medical practice, in favor of federal control.
We've been scared from using antibiotics and antivirals out of some kind of weird sense of communal responsibility to keep bugs naive to our powerful weapons.
Limiting Covid's impact requires us to think differently about confronting respiratory pathogens in the winter.
The first nation to develop a vaccine for Covid-19 could have an economic advantage as well as a tremendous public-health achievement. Doses will be limited initially as suppliers ramp up, and a country will focus on inoculating most of its own population first.
It once seemed that the most profound feats stemming from DNA-based science would spring from our ability to read and detect genes, which we call the science of genomics. But the real opportunities lie in our ability to write DNA, to synthesize new gene sequences and insert them into organisms, resulting in brand-new biological functions.
Historical records show that smallpox was a human scourge for thousands of years. The virus produces high fever, severe back pain and scarring eruptions of flat red spots on the skin that turn into pustules and then into scabs - a two-week process during which the disease is highly contagious.
At the heart of President Barack Obama's health-care plan is an insurance program funded by taxpayers, administered by Washington, and open to everyone. Modeled on Medicare, this 'public option' will soon become the single dominant health plan, which is its political purpose. It will restructure the practice of medicine in the process.
Advocacy groups like Families U.S.A. imagine that once Medicaid becomes a middle-class entitlement, political pressure from middle-class workers will force politicians to address these problems by funneling more taxpayer dollars into this flawed program. President Barack Obama's health plan follows this logic.
America tolerates a heavy toll from the flu on health and productivity. But if Covid becomes a twin risk, the heath-care system will struggle to fight both at once.
Biologics must be grown in living systems - fermented, for example, in large vats of bacteria cells. This makes them hard to replicate. For decades, biologics weren't subject to competition from copycat generic medicines, even once patents and exclusivities had lapsed on originals.
The truth is that the greatest innovations in health-care delivery haven't come from federally contrived oligopolies or enormous hospital chains. Novel concepts - whether practice-management companies, home health care or the first for-profit HMO - almost always have come from entrepreneurial firms, often backed by venture capital.
Among the most common reasons why people come to an emergency room are bouts of heart failure or pneumonia. Sometimes they have a touch of both.
In countries such as France and Germany, layers of bureaucracy like health boards have been specifically engineered to delay the adoption of new medical products and services, thus lowering spending.
Gene editing will be used to alter DNA to erase the origins of a range of debilitating inherited disorders.
A respiratory pathogen may pose an asymmetric risk to America, given our culture, economy and federalist system.
A seductive technology that works like a dream and improves lives will set off a consumer clamor, whether the new tool is an iPhone 4S or an implantable blood-sugar meter.
Our Founders thought politicians should be accountable when it comes to citizens' right to life, liberty and the pursuit of heart surgery.
The key to the generic-drug economic model is to keep entry prices low enough to attract multiple competitors.
Reformers in Washington need to do a better job of explaining how market-based alternatives to ObamaCare are a better outcome for the structure and delivery of health care.
Smallpox can be personally devastating. After a 14-day incubation period, patients experience high fevers, headaches, and sometimes severe abdominal pain. A rash resembling chicken pox appears in the mouth and throat, face, and forearms, and spreads to the trunk and legs. As patients recover, scabs break and pitted scars appear.
Rather than redistribute physician income as a way to subsidize an expansion of government control, Mr. Obama should fix the payment system to align incentives with improved care.
If drug development becomes the domain of government researchers, it's a sure bet that political lobbying will eventually trump scientific promise and commercial viability when it comes to investment decisions.
The higher cost of getting a generic drug approved by regulators means that many old medicines don't face competitors. It's only after substantial price hikes that these drugs offer enough revenue to offset the rising generic entry costs, and start to entice competition.
A true legislative alternative to ObamaCare would support physician ownership of independent medical practices, and preserve local competition between doctors and choice for patients.
Once an effective drug is approved to treat a deadly condition, introducing a second drug to treat the same disease can be hard. It's tough to recruit patients with a debilitating disease for a clinical trial when a proven medicine is already available.
Covid is likely to persist once its pandemic phase has passed and circulate each winter alongside the flu. Even after more of us contract coronavirus infection and develop immunity to it or even after an effective vaccine arrives, some people will still get very sick.
More government control of doctors and their reimbursement schemes will only create more problems.
The fact is, many poor patients visit ERs simply because they don't have a family doctor.
One option is to run Medicaid like a health program - rather than an exercise in political morals - and let states tailor benefits to the individual needs of patients, even if that means abandoning the unworkable myth of 'comprehensive' coverage.
America is home to a vast, dynamic life-science industry.
Printing novel DNA might open the way to achievements once only conceivable in science fiction: designer bacteria that can produce new chemicals, such as more efficient fuels, or synthetic versions of our cells that make us resistant to the effects of radiation.
Regulators at the Food and Drug Administration have a tough job.
One of the biggest factors fueling the angst over drug prices in the U.S. is that some older medicines that should be sold cheaply as generics are still priced very high, often owing to a dwindling number of generic competitors and the rising cost of producing these drugs.
There's instinctual discomfort about using evidence of past immunity as a factor for decisions about health, work or even questions like whether it's safe to visit someone in a nursing home. But there are ways to deploy immunity information to help us understand our own health status and keep us safer from Covid, without surrendering privacy.
There are two main types of immunity to an infection. Innate immunity comes from circulating cells that attack any invader the body views as foreign. Adaptive immunity is specific to the pathogen presented. Through adaptive response, immune cells are programmed to secrete antibodies that are primed to target a viral invader.
ObamaCare has accelerated many of the detrimental trends doctors see in their profession, and introduced new ones.
The authors of the Affordable Care Act wrongly assumed that new kinds of health plans, engineered in Washington, D.C., would emerge to displace the national for-profit insurers.
Why do physicians prescribe powerful antibiotics? Generally not because our patients ask for them. Most people who come in with a sore throat would be just as happy leaving my office with a prescription for Chloraseptic as clarithromycin.
It is true that some off-label drug use is based on very unsettled science and has more risks. But medicine - and not just cancer care - involves lots of hard choices. And the more serious the disorder, often the more likely it is that for every right and wrong treatment choice there are many other practical decisions painted in shades of gray.
Antibiotic resistance is as old as the dirt that coats our planet.
Americans broadly consent to funding clinical research because they believe in the promise of medical research. But people support scientific work only if they trust that it serves societal interests, respects patient dignity and operates with guardrails.
When I was a medical student, a pulmonary professor of mine cajoled me into joining a clinical trial that she was running. The general aim of the tests was to determine whether prolonged periods of short and shallow breathing would cause a person's lungs to go into spasm. It turns out, as I can attest, that they do.
One thing about Covid-19 is clear: We don't fully understand its severity and transmission. At various turns, we've both underestimated and overestimated the virus.
Policies I advanced as FDA commissioner aimed to get smokers off cigarettes and onto less-harmful forms of nicotine delivery.
In 'Pox: An American History,' Michael Willrich meticulously traces the story of how the smallpox vaccine was pressed into service during a major outbreak.
It's important to protect the old and the vulnerable, who are at the highest risk of severe illness and bad outcomes. But like most issues of medicine, it isn't a binary choice. Given the uncertainties of how this virus spreads and its high risk of infirmities, it would be unwise to abandon efforts to limit Covid spread wherever possible.
Covid-19 may be here for a long time.
When the price of a drug rises, it becomes profitable and the target of new competition.
Politicians wage broad wars on medicine to claim thin strips of ideological terrain. This would be good political theater if there weren't so many human victims.
Patients would be better off if states were able to tailor the benefits that Medicaid covers - targeting resources to sicker people and giving healthy adults cheaper, basic coverage.
When people age, the main valve carrying blood out of the heart becomes brittle. As this aortic valve narrows, it can cause debilitating heart failure, and even death.
Confronting a dangerous pandemic requires containing spread wherever it is reasonably possible. Sensible measures such as universal masking, testing and widespread and rapid contact tracing can help. The best way to protect the vulnerable is to try to protect everyone.
Covid-19 has altered world history.
Health-assessment software such as CareEvolution's 'Safer Covid' tool can combine multiple health factors to evaluate a person's total risk of contracting Covid or suffering a bad outcome.
The convergence of information technology and biology allows scientists to translate the human genome into digital data that can accelerate diagnoses and cures.
It's now evident that public health is part of national security.
Covid spreads too easily to think it can be confined to the young.
Cell-based and regenerative medicine can restore human functions lost to disease, including returning some sight to the blind.
When gene therapy was believed to harbor latent risks, research was largely put on hold until the risks were better understood. Sometimes, the theoretical risks have led to a principle of absolutist precaution that impedes progress.
In fast moving fields like cancer, where doctors tailor treatments based on evidence that's constantly evolving, two years can be an eternity of waiting to learn about important science. For some patients, that interval can be fatal.
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