William Stewart Halsted, M.D. was an American surgeon who emphasized strict aseptic technique during surgical procedures, was an early champion of newly discovered anaesthetics, and introduced several new operations, including the radical mastectomy for breast cancer. Along with William Osler, Howard Atwood Kelly and William H. Welch, Halsted was one of the "Big Four" founding professors at the Johns Hopkins Hospital. His operating room at Johns Hopkins Hospital is in Ward G, and was described as a small room where medical discoveries and miracles took place. According to an intern who once worked in Halsted's operating room, Halsted had unique techniques, operated on the patients with great confidence and often had perfect results which astonished the interns.