A Quote by Cesar Milstein

Back in 1962, when I had by accident become the supervisor of Roberto Celis in Argentina, it occurred to me that antibody diversity might arise from the joining by disulphide bridges of a variety of small polypeptides in combinatorial patterns.
The study of the amino acid sequence around the disulphide bonds of the immunoglobulins was my own short-cut to the understanding of antibody diversity.
What attracted me to immunology was that the whole thing seemed to revolve around a very simple experiment: take two different antibody molecules and compare their primary sequences. The secret of antibody diversity would emerge from that. Fortunately at the time I was sufficiently ignorant of the subject not to realise how naive I was being.
Bridges are burning all around us; bridges to responses that might have mitigated the already brutal (and just beginning) ravages of Peak Oil; bridges to reduce the likelihood of war and famine; bridges to avoid our selectively chosen suicide; bridges to change at least a part of energy infrastructure and consumption; bridges to becoming something better than we are or have been; bridges to non-violence. Those bridges are effectively gone.
And it dawned on me that I might have to change my inner thought patterns... that I would have to start believing in possibilities that I wouldn't have allowed before, that I had been closing my creativity down to a very narrow, controllable scale... that things had become too familiar and I might have to disorientate myself. p.71
What humans do with the language of mathematics is to describe patterns... To grow mathematically children must be exposed to a rich variety of patterns appropriate to their own lives through which they can see variety, regularity, and interconnections.
The sense of community does not arise out of collective movement, nor from conforming to some group direction. Quite the contrary. Each individual tends to use the opportunity to become all that he or she can become. Separateness and diversity - the uniqueness of being "me" - are experienced
I left my frogs, which I had grown, with my supervisor, who had moved to Geneva, and he and a technician grew them up. So by 1962, they were adults, and one could publish a paper to say that these animals, derived from nuclear transfer, really were absolutely normal. So it took a little time to get through.
I arrived back in Argentina and a week after I had the offer from Arsenal. They called my agent and my family and I thought it was all about signing a new contract for my club in Argentina because they wanted to offer me one at the time, but it was actually to sign for Arsenal.
There's no use diversifying into unknown companies just for the sake of diversity. A foolish diversity is the hobgoblin of small investors. That said, it isn't safe to own just one stock, because in spite of your best efforts, the one you choose might be the victim of unforeseen circumstances. In small portfolios, I'd be comfortable owning between three and ten stocks.
I never expected to become a director. It never occurred to me to come to America, to Hollywood. It's all been a wonderful accident. I'm still amazed every time I finish a film.
There are only patterns. Patterns on top of patterns, patterns that affect other patterns, patterns hidden by patterns, patterns within patterns.
There are only patterns, patterns on top of patterns, patterns that affect other patterns. Patterns hidden by patterns. Patterns within patterns. If you watch close, history does nothing but repeat itself. What we call chaos is just patterns we haven't recognized. What we call random is just patterns we can't decipher. what we can't understand we call nonsense. What we can't read we call gibberish. There is no free will. There are no variables.
The idea that skiing might not be fun, might not be for everyone, had never occurred to me. Where I come from, the sport signified pleasure, nature, family happiness.
Never had it occurred to me that the things that had happened to me...might be a kind of trauma.
We're looking at such enormous complexity and variety that it makes a mockery of "celebrating diversity." In the L.A. of the future, no one will need to say, "Let's celebrate diversity." Diversity is going to be a fundamental part of our lives. That's what it's going to mean to be modern.
The production of antibody is not the only, nor I believe the most important, manifestation of immunity, but for reasons both historical and of experimental convenience, antibody is likely to remain the touchstone of immunological theory.
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