A Quote by Craig Venter
I think I've achieved some good things; doing the first genome in history - my team on that was phenomenal and all the things they pulled together; writing the first genome with a synthetic cell; my teams at the Venter Institute, Human Longevity, and before that Celera.
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Every cell in our body, whether it's a bacterial cell or a human cell, has a genome. You can extract that genome - it's kind of like a linear tape - and you can read it by a variety of methods. Similarly, like a string of letters that you can read, you can also change it. You can write, you can edit it, and then you can put it back in the cell.
The first thing you have to do is to sequence the Neanderthal genome, and that has actually been done. The next step would be to chop this genome up into, say, 10,000 chunks and then... assemble all the chunks in a human stem cell, which would enable you to finally create a Neanderthal clone.
If you get a personal genome, you should be able to get personal cell lines, stem cell derived from your adult tissues, that allow you to bring together synthetic biology and the sequencing so that you can repair parts of your body as you age or repair things that were inherited disorders.
The question is, are there useful things that we can do with the results of a genome sequence that would bring benefit? And the answer is, today, should the majority of people go and have their genome sequenced? Probably not. But are there particular circumstances in which genome sequencing is really helpful? Yes, there are.
The mouse genome is an invaluable tool to interpret the human genome.
One of the big challenges now is to figure out just how many viruses there really are in the human genome. So far the estimate is 8.3% of our genome is virus, but it actually could be a lot higher.
People think that Celera's trying to patent the whole human genome because it's been used as - I guess people in Washington learn how to do political attacks, and so it gets used as a political weapon, not as a factual one.
As a Christian, but also as a scientist responsible for overseeing the Human Genome Project, one of my concerns has been the limits on applications of our understanding of the genome. Should there be limits? I think there should. I think the public has expressed their concern about ways this information might be misused.
If you know the mother's genome and the father's genome, and you see that the children have some genes that neither parent has, then you know that difference is either a mutation or a processing error.
Obviously, things evolve; teams see you play a little bit and start try to do things, and the one thing that'll happen is if one team has success in something, you can bet the next three teams are doing some similar things, too.
We have 200 trillion cells, and the outcome of each of them is almost 100 percent genetically determined. And that's what our experiment with the first synthetic genome proves, at least in the case of really simple bacteria. It's the interactions of all those separate genetic units that give us the physiology that we see.
Some software is actually pretty good, by any standard. Think of the Mars Rovers, Google, and the Human Genome Project. Now, that's quality software!
There's always a question when you invest. Are you too early, are you too late, or are you just right? And there was a lot of hype about life sciences, around the sequencing of the human genome and a lot of people concluded that's not really there. But by the way, there was a lot of hype around the digital revolution just about the time of 2000 and the human genome, and it turns out that some of the world's biggest, most powerful companies are the survivors post that crash.
What I really wanted was for everybody to have their genome and, ideally, everybody to share their genome, and for that, we needed to bring the price way down.
We are here to celebrate the completion of the first survey of the entire human genome. Without a doubt, this is the most important, most wondrous map ever produced by human kind.
Why do people believe that there are dangerous implications of the idea that the mind is a product of the brain, that the brain is organized in part by the genome, and that the genome was shaped by natural selection?
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