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The emergence of a unified cognitive moment relies on the coordination of scattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distributed anatomical and functional organization of brain activity to enable the emergence of coherent behaviour and cognition. Although the mechanisms involved in large-scale integration are still largely unknown, we argue that the most plausible candidate is the formation of dynamic links mediated by synchrony over multiple frequency bands.
A large-scale wind, water and solar energy system can reliably supply the world’s needs, significantly benefiting climate, air quality, water quality, ecology and energy security ... [T]he obstacles are primarily political, not technical.
It's a lot easier to figure out how to scale something that doesn't feel like it would scale than it is to figure out what is actually gonna work. You're much better off going after something that will work that doesn't scale, then trying to figure how to scale it up, than you are trying to figure it all out.
Small-scale fisheries should not be favoured over large-scale operations ebcause of romantic notions of rugged small operators battling both the elements and anonymous corporations. [They ought to be supported] because of the scientific evidence available to confirm the common-sense inference that local fishers, if given privileged access, will tend to avoid trashing their local stocks, while foreign fishers do not have such motivation.
The frontiers of science, on the very small scale and very large scale, require large investments and international effort.
The most essential mental quality for a free people, whose liberty is to be progressive, permanent and on a large scale, is much stupidity.
Any large-scale organization must lose some of the merits of its rudimentary beginnings. Quantity will have a coarsening effect on quality.
Americans often did not realize that their Marine Corps was a force without counterpart in the world. European navies used Marines for limited duties on shipboard or in naval bases, but neither the numbers nor the training were provided for large-scale offensive operations.
Testing by itself does not improve software quality. Test results are an indicator of quality, but in and of themselves, they don't improve it. Trying to improve software quality by increasing the amount of testing is like trying to lose weight by weighing yourself more often. What you eat before you step onto the scale determines how much you will weigh, and the software development techniques you use determine how many errors testing will find. If you want to lose weight, don't buy a new scale; change your diet. If you want to improve your software, don't test more; develop better.
The observation that money changes induce output changes in the same direction receives confirmation in some data sets but is hard to see in others. Large-scale reductions in money growth can be associated with large-scale depressions or, if carried out in the form of a credible reform, with no depression at all.
With things that I'm going through, whether they be on a small scale or a large scale, I'm thinking, 'Who else is going through this? And how can I address it and bring it to light to help someone else?'
Everything that can be found in the universe on a large scale is reflected in a human being on a small scale.
From building a fire one can learn something about artistic composition. If you use only small kindling and large logs, the fire will quickly eat up the small pieces but will not become strong enough to attack the large ones. You must supply a scale of sizes from the smallest to the largest. The human eye also will not make its way into a painting or building unless a continuum of shapes leads from the small to the large, from the large to the small.
We've organized ourselves as cultures, to a large degree, around what we agree we know. And when you have multiple ways of knowing, multiple ways of organizing, the society loses one of its deepest organizational principles.
It is the multiplication of men who are exluded from working which provokes war. We ought at least to bear this in mind when we boast of the continual decrease in human participation in technical operations.