A Quote by Francis Crick
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
We can do genetics. We can do experiments on fruit flies. We can do experiments on yeast. It's not so easy to do experiments on humans. So, in fact, it helps us, to interpret our own genetic code, to have the genetic code of the other species.
In general, the more one augments the number of divisions of the productions of nature, the more one approaches the truth, since in nature only individuals exist, while genera, orders, and classes only exist in our imagination.
When we cracked the genetic DNA code, opened the big Pandora's box, and it really did become possible to produce chimeras, my ears shot up. Having been brought up among the biologists and having followed various debates about ways to improve the human template and other debates about the true nature of our nature, I began seriously to wonder: What if? We hold in our hands a tool that is more powerful - for good or ill - than any we have wielded before.
The simplicity of nature is not to be measured by that of our conceptions. Infinitely varied in its effects, nature is simple only in its causes, and its economy consists in producing a great number of phenomena, often very complicated, by means of a small number of general laws.
The way to secure peace is to be prepared for war. They that are on their guard, and appear ready to receive their adversaries, are in much less danger of being attacked, than the supine, secure, and negligent.
Information is crucial to our biological substance - our genetic code is information. But before 1950, it was not obvious that inheritance had anything to do with code. And it was only after the invention of the telegraph that we understood that our nerves carry messages, just like wires.
The genetic code is not a binary code as in computers, nor an eight-level code as in some telephone systems, but a quaternary code with four symbols. The machine code of the genes is uncannily computerlike.
If you take away scale, the nature of the story changes. I made a joke the other day: if I were to try to make 'Glory' now, rather than be about a regiment, it would be about a platoon. It would be seven men in the woods rather than all the men on the beach.
If we could survive without a wife, citizens of Rome, all of us would do without that nuisance; but since nature has so decreed that we cannot manage comfortably with them, nor live in any way without them, we must plan for our lasting preservation rather than for our temporary pleasure.
The knowledge of Natural-History, being Observation of Matters of Fact, is more certain than most others, and in my slender Opinion, less subject to Mistakes than Reasonings, Hypotheses, and Deductions are; ... These are things we are sure of, so far as our Senses are not fallible; and which, in probability, have been ever since the Creation, and will remain to the End of the World, in the same Condition we now find them.
Departure from the literal aspect, rather than mechanical exactness, is the code of the true artist. However, departures are the result of studied intent rather than inability.
All Nature is linked together by invisible bonds and every organic creature, however low, however feeble, however dependent, is necessary to the well-being of some other among the myriad forms of life.
Simple assent to the gospel, divorced from a transforming commitment to the living Christ, is by Biblical standards less than faith, and less than saving, and to elicit only assent of this kind would be to secure only false conversions.
Healing is a coming to terms with things as they are, rather than struggling to force them to be as they once were, or as we would like them to be, to feel secure or to have what we sometimes think of as our own way.
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