Sometimes you have to say no to things that people don't want you to say no to in the interest of self-preservation. I definitely went through some times that I did more than I could handle, and I was trying to make decisions for the best of my career; the irony was that those decisions were a direct cause of my inability to produce, perform, create anything. If you are not emotionally and personally stable and intact and healthy, then the entire foundation of what you do this for - the things that you make - is gone.