A Quote by Andrew Solomon
It's important to say that depression has biological underpinnings, and that while medications do not seem to create irreversible changes in the brain, repeated depressive episodes do.
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I want good science, and I want it to be realistically marketed. I wouldn't like only two countries on the planet that allow pharmaceutical companies to market directly to people, New Zealand and the United States. It ought to be better regulated. And when it's presented to people, it ought to be presented in a way that's realistic. For example, often people will prescribe antidepressant medications, and we'll say, you have a brain disease; you'll have to be on these medications permanently. There is no biological marker for depression. It's not true that we know that it's a brain disease.
There is no common standard for education about diagnosis. Distinguishing between bipolar depression and major depressive disorder, for example, can be difficult, and mistakes are common. Misdiagnosis can be lethal. Medications that work well for some forms of depression induce agitation in others.
I suffer from manic-depressive disorder, and I've chosen not to take medication for it. Because of that, every once in a while I go through manic episodes and really depressed episodes.
The point about manic depression or bipolar disorder, as it's now more commonly called, is that it's about mood swings. So, you have an elevated mood. When people think of manic depression, they only hear the word depression. They think one's a depressive. The point is, one's a manic-depressive.
I'd definitely say I'm a depressive, someone who suffers from depression.
What politicians want to create is irreversible change because when you leave office someone changes it back again.
I am a rapid-cycling manic-depressive, bi-polar one disorder, which means I can have thirty or forty episodes a year, and I used to have thirty to forty episodes a year.
A long iron rod rocketed straight through the very forefront of Phineas Gage's brain. It's kind of an unusual part of the brain: you can suffer pretty severe injuries to it and often walk away from the injury. It's not a part of the brain that's necessarily vital for your biological self. But it is very important for personality.
A Soviet man is a product of invisible changes, degradation and progressive deformation. Breaking the chain of those changes is hard. Perhaps they are irreversible.
Antidepressant medications, you still have some depressive thoughts. Antipsychotic medications, you still have some psychotic symptoms for the vast majority of the people taking them. But it gives them a little separation, and it doesn't control his behavior as much when you have a sad feeling, difficult thought, an odd perceptual experience. We can teach people those exact skills in therapy, you get longer-term benefits and without the side effects. So don't be sold just because a commercial interest wants to sell you things.
Both depression and anxiety disorders, for example, are repeatedly described in the media as 'chemical imbalances in the brain,' as if spontaneous neural events with no relation to anything outside a person's brain cause depression and anxiety.
If you have a little sensibility or a heart, you have all the reason to be depressed once in a while. But the depression is like a motor for creation. I need a little bit of depression, a bit of acid in my stomach, to be able to create. When I'm happy, I just want to dance.
The climate is nearing tipping points. Changes are beginning to appear and there is a potential for explosive changes, effects that would be irreversible, if we do not rapidly slow fossil-fuel emissions over the next few decades.
The prescribers very often overstate, oversell, and the detail people are only too happy to tell them to do that. This idea that there's something wrong with your brain, and by the way, almost never are these antidepressant medications evaluated with what will happen if you're on them for three, four, five, 10, 15 years. Sometimes some of the side effects that come up come up only later, and sometimes they're very severe, even irreversible side effects.
As a teenager, I struggled a lot, had several major depressive episodes, and ended up dropping out of high school and getting a GED.
So many people are struggling to create happiness while their brain is inundated by noise. If your brain is receiving too much information, it automatically thinks you're under threat and scans the world for the negative first. Because the brain is limited, whatever you attend to first becomes your reality.
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