A Quote by Carl Zimmer
About 1.2% of the human genome is made up of genes, things that encode for proteins, the stuff that we consider us. There is about 8.3% that's a virus. In other words we're probably about seven times more virus than we are human genes, which is kind of a weird way to thinking about yourself.
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We have Borna virus genes. We're part Borna virus, which is weird, but apparently our cells and our genomes in a weird way might actually be grabbing these viruses, grabbing genetic material from the viruses that are infecting it and pulling them into their own genome.
Genes are effectively one-dimensional. If you write down the sequence of A, C, G and T, that's kind of what you need to know about that gene. But proteins are three-dimensional. They have to be because we are three-dimensional, and we're made of those proteins. Otherwise we'd all sort of be linear, unimaginably weird creatures.
Human beings are ultimately nothing but carriers-passageways- for genes. They ride us into the ground like racehorses from generation to generation. Genes don't think about what constitutes good or evil. They don't care whether we are happy or unhappy. We're just means to an end for them. The only thing they think about is what is most efficient for them.
In the late 1970s, when I was a professor at Caltech, I pioneered four instruments for analyzing genes and proteins that revolutionized modern biology - and one of these, the automated DNA sequencer, enabled the Human Genome Project.
Recently, results of the Human Genome Project have shattered one of Science's fundamental core beliefs, the concept of genetic determinism. We have been led to believe that our genes determine the character of our lives, yet new research surprisingly reveals that it is the character of our lives that controls our genes. Rather than being victims of our heredity, we are actually masters of our genome.
It used to be thought that only a certain kind of virus could get into our genome and it's called a retrovirus and that's a virus that might be HIV for example.
Realizing the ways in which we humans may have been inadvertently changing our genes for millennia provides a way for us to begin to think about the inevitable genetic revolution in medicine that is going to allow us to advertently change our genes over centuries and even decades.
A DNA sequence for the genome of bacteriophage ?X174 of approximately 5,375 nucleotides has been determined using the rapid and simple 'plus and minus' method. The sequence identifies many of the features responsible for the production of the proteins of the nine known genes of the organism, including initiation and termination sites for the proteins and RNAs. Two pairs of genes are coded by the same region of DNA using different reading frames.
A virus is not just DNA; a virus is also packaged up, covered over with a series of proteins in a nice, elegant, well-compacted form.
All the work on heritability was never based on looking at genes; it was based on the similarity between identical twins or between parents and children. Now that geneticists can look at genes, they can't find genes that account for more than 10 percent of the variation in any human trait.
It's a very complex network of genes making products which go into the nucleus and turn on other genes. And, in fact, you find a continuing network of processes going on in a very complex way by which genes are subject to these continual adjustments, as you might say - the computer programmer deciding which genes ultimately will work.
I think we have other things to worry about than some Zika virus.
One of the big challenges now is to figure out just how many viruses there really are in the human genome. So far the estimate is 8.3% of our genome is virus, but it actually could be a lot higher.
With regard to the alternatives, we already have them. The cellular and genetic lines of research in humans are the most promising. AIDS is caused by a virus, so it makes sense to study the virus, not chimpanzees. We have learned virtually nothing about AIDS from the chimpanzee. Every major advance in AIDS research ... has come from human studies.
Charles Darwin and I and you broke off from the family tree from chimpanzees about five million years ago. They're still our closest genetic kin. We share 98.8 percent of the genes. We share more genes with them than zebras do with horses. And we're also their closest cousin. They have more genetic relation to us than to gorillas.
It is fashionable to wax apocalyptic about the threat to humanity posed by the AIDS virus, "mad cow" disease, and many others, but I think a case can be made that faith is one of the world's great evils, comparable to the smallpox virus but harder to eradicate.
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