A Quote by Charles Scott Sherrington

If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.
It is always understood as an expression of condemnation when anything in Literature or Art is said to be done for effect; and yet to produce an effect is the aim and end of both.
The aim and end of the artist is not truth exactly, much less fact; it is effect... There is no doubt he [the photographer] best gets his effect by way of truth, but he uses it as he would a servant, not a master.
I define a Sign as anything which is so determined by something else, called its Object, and so determines an effect upon a person, which effect I call its Interpretant, that the latter is thereby mediately determined by the former.
In effect, dividing your attention means that neither (or none) of the things you're working on is really getting the full effect of your intelligence, and that it in the end takes you longer than it would if you did one thing at a time.
The way I see it, when you put the uniform on, in effect you sign a contract. And you don't back out of a contract merely because you've changed your mind. You can still speak up for your principles, you can still argue against the ones you're being made to fight for, but in the end you do the job.
The end of poetry is not to create a physical condition which shall give pleasure to the mind... The end of poetry is not an after-effect, not a pleasurable memory of itself, but an immediate, constant and even unpleasant insistence upon itself.
In macroeconomic theory, there is this argument that what the Fed does has no effect on unemployment, no effect on investment, no effect on the rate of GDP growth.
To identify yourself with your personality is more or less a reflex. You must see, when the reflex comes up, that it is a kind of feeling of insecurity; you are looking for a hold.
Thought reflexes get conditioned very strongly, and they are very hard to change. And the also interfere. A reflex may connect to the endorphins and produce an impulse to hold that whole pattern forther. In other words, it produces a defensive reflex. Not merely is it stuck because it's chemically so well built up, but also there is a defensive reflex which defends against evidence which might weaken it. Thus it all happens, one reflex after another after another. It's just a vast system of reflexes. And they form a 'structure' as they get more rigid.
Love is a positive effect. Love can never have a negative effect, only a positive effect. That would be the revelation of love. If you have a question of whether this is love, think about the effect.
Cause and effect, means and ends, seed and fruit cannot be severed; for the effect already blooms in the cause, the end preexists in the means, the fruit in the seed
Tragedy is an imitation not only of a complete action, but of events inspiring fear and pity. Such an effect is best produced when the events come on us by surprise; and the effect is heightened when, at the same time, they follow as cause and effect. The tragic wonder will then be great than if they happened of themselves or by accident; for even coincidences are most striking when they have an air of design.
She wore tight corsets to give her a teeny waist - I helped her lace them up - but they had the effect of causing her to faint. Mom called it the vapors and said it was a sign of her high breeding and delicate nature. I thought it was a sign that the corset made it hard to breathe.
You see, unlike in the movies, there is no THE END sign flashing at the end of books. When I've read a book, I don't feel like I've finished anything. So I start a new one.
The imagination loses vitality as it ceases to adhere to what is real. When it adheres to the unreal and intensifies what is unreal, while its first effect may be extraordinary, that effect is the maximum effect that it will ever have.
One should not wrongly reify 'cause' and 'effect,' as the natural scientists do (and whoever, like them, now 'naturalizes' in his thinking), according to the prevailing mechanical doltishness which makes the cause press and push until it 'effects' its end; one should use 'cause' and 'effect' only as pure concepts, that is to say, as conventional fictions for the purpose of designation and communication-not for explanation.
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