A Quote by Francis Collins
A lot of science doesn't require big "ns" but if you're trying to understand something about human health and you're looking at interventions that are not going to be either killing you or making you live forever - they're going to have some tweaking on the outcome - you need big numbers or you don't have enough power.
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I knew that's where I was going. I knew we were going to Italy. You couldn't make this movie in America at this price. I knew it was going to be big. I knew there was going to be a ship involved and that there was going to be a set as big as the ship. I thought, well, here we go. But I knew that was where he was headed. He had been going this way for some time. All directors, once they have some success, they want to spend a whole heck of a lot of money. (Something else can't hear.)
If I was diagnosed with something that was fatal in the next couple of years, I can't imagine anything more terrifying. And so for me, we know a lot about technology and we know a lot about the world, but I think health is the one area where there's so much data, but it's chaotic and that it's still a big black box. So, understanding really what is going to make me healthy and what is going to allow me to live the longest life is definitely keeps me up.
You need to know a lot about what's going on, but when it comes to making the work, I take almost an anti-intellectual stance. You've got to be stupid enough, in some ways, to plunge into something that you have no idea what it's about. If you know what you're going to do before you do it, you just end up illustrating an idea.
When you write a program, think of it primarily as a work of literature. You're trying to write something that human beings are going to read. Don't think of it primarily as something a computer is going to follow. The more effective you are at making your program readable, the more effective it's going to be: You'll understand it today, you'll understand it next week, and your successors who are going to maintain and modify it will understand it.
Boom and bust cycles are very difficult for businesses because you're hiring a bunch because you're planning for the future. And if the future is going to be very big, you need to hire people, or suddenly you go to boom to bust, then all of a sudden, you're kind of battening down the hatches and trying to sail, you know, through the storm, it's a different thing. So part of it is making good decisions about, well, how long is a boom cycle going to be, you know, don't plan on it going forever.
Our culture is making a big difference and, whether it's our curries or movies like "Slumdog Millionaire" or whether it's just the Bollywood numbers to which a lot of the world is rocking, I think India's soft power is going up. And we are contributing a lot of entrepreneurs to the world as well whether it's people like Lakshmi Mittal or Indra Nooyi or thinkers like Amalti Singh. This is all happening because of there's something fundamentally right and thoughtful about Indian society.
I pick my feature film battles very carefully. They're going to be personal and they're going to take a lot of my energy. I'm not going to be some big production company and be Jerry Bruckheimer or something like that. It doesn't interest me.
My poll numbers are going through the roof. You know why? I really believe a big part of it is Obamacare, because we`re going to repeal it and replace it. Obamacare has to be replaced. And we will do it and we will do it very, very quickly. It is a catastrophe. If we don`t repeal and replace Obamacare, we will destroy American health care forever.
Donald Trump is going to win. Donald Trump is going to win because in the end, the country is not going to reward big banks and big unions and big bureaucracies and big donors and big corruption by voting for a big liar.
I think, a lot of time, when I'm making art, I'm trying to get into a state of childlike play, where I'm not self-conscious; I'm not worried about what the outcome is going to be. I'm just having fun.
So now I'm going to forget the 400 years of lynching and killing raping and depriving my people feeding of justice and equality and the lowest of low last respect and I'm going to look at two or three white people who are trying to do right and don't see the other million who are trying to kill me? I'm not that big of a fool.
I remember Ozzy Osbourne making a fuss on The Osbournes - people were making a big deal about him taking the garbage out, and he said, "Well, who else is going to do it?" The garbage is full, and you're standing right there. You're still a human being who is going to make yourself a sandwich.
As an actor, I enjoy variety. That's a big thing for me. So, if I'm going to put my name to something and commit to something that's going to take up a lot of my time, it has to be something that I know is going to be enjoyable and worth my while. Otherwise, what's the point?
What is the most powerful force in the world? And I think you would agree that is a big idea if it is in the hands of an entrepreneur who is actually going to make the idea not only happen, but spread all across society. And we understand that in business but we have need for entrepreneurship just as much in education, human rights, health, and the environment as we do in hotels and steel.
Then something fails and they're all out again, but DVD revenue is disappearing, you know, it's not disappearing but it's going off a cliff and what that's done is it's polarized the industry in a way that I've never seen before where studios are making less, they're bifurcating their choices where they're either going very, very big or they're just picking up a few rights on an acquisition basis or making really small things.
I've always mid-lined myself where I don't really expect myself to do big things or to win big fights. It's not a lack of confidence, it's just that I think to an extent that you need a bit of an ego if you're going to think that you're going to conquer something.
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