A Quote by Francis Crick

If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap.
To govern is to correct. If you set an example by being correct, who would dare to remain incorrect?
The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.
First shalt thou take out the Holy Pin. Then shalt thou count to three, no more-no less. Three shall be the number thou shalt count, and the number of the counting shall be three. Four shalt thou not count, neither count thou two, excepting that thou then proceed to three. Five is right out. Once the number three, being the third number, be reached, then lobbest thou thy Holy Hand Grenade of Antioch towards thy foe, who, being naughty in my sight, shall snuff it.
If I go for the alternative which is false, then obviously I shall be in error; if I take the other side, then it is by... chance that I arrive at the truth, and I shall still be at fault.... In this incorrect use of free will may be found the privation which constitutes the essence of error.
Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
According to the celestial multiplication table, once one is three, and three times one is one, and according to heavenly subtraction if we take two from three, three are left. The addition is equally peculiar, if we add two to one we have but one. Each one is equal to himself and the other two.
Decide, before you start, that you're going to change three things about what you do all day at work. Then, as you're reading, find the three things and do it. The goal of the reading, then, isn't to persuade you to change, it's to help you choose what to change.
The history of science is rich in example of the fruitfulness of bringing two sets of techniques, two sets of ideas, developed in separate contexts for the pursuit of new truth, into touch with one another.
The big thing is, everybody says it's being in the right place at the right time. But it's more than that, it's being in the right place all the time. Because if I make 20 runs to the near post and each time I lose my defender, and 19 times the ball goes over my head or behind me - then one time I'm three yards out, the ball comes to the right place and I tap it in - then people say, right place, right time. And I was there *all* the time.
All directors on all sets behave slightly differently depending on what the scene is. For example, if you are doing a love scene, which is intimate then the director is likely to be intimate. If you are doing a scene where everyone is mucking around and laughing then the director is likely to start with that. If you are playing a scene which us incredibly heavy and everyone getting killed then there are probably not many laughs on the set.
I doubt if I shall ever have time to read the book again -- there are too many new ones coming out all the time which I want to read. Yet an old book has something for me which no new book can ever have -- for at every reading the memories and atmosphere of other readings come back and I am reading old years as well as an old book.
Now, everybody knows the basic erogenous zones. You got one, two, three, four, five, six, and seven. ... OK, now most guys will hit one, two, three and then go to seven and set up camp. ... You want to hit 'em all and you wanna mix 'em up. You gotta keep 'em on their toes. ... You could start out with a little one. A two. A one, two, three. A three. A five. A four. A three, two. Two. A two, four, six. Two, four, six. Four. Two. Two. Four, seven! Five, seven! Six, seven! Seven! Seven! Seven! Seven! Seven! Seven! Seven! Seven! Seven! [holds up seven fingers]
We must wholeheartedly believe in free will. If free will is a reality, we shall have made the correct choice. If it is not, we shall still not have made an incorrect choice, becauee we shall not have made any choice at all, not having a free will to do so.
No one set that I ever do is the same. I mean, if I go to a comedy club, and I perform three sets, all three sets are different because anything can happen in between sets.
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