A Quote by George E. P. Box

One important idea is that science is a means whereby learning is achieved, not by mere theoretical speculation on the one hand, nor by the undirected accumulation of practical facts on the other, but rather by a motivated iteration between theory and practice.
From the dawn of exact knowledge to the present day, observation, experiment, and speculation have gone hand in hand; and, whenever science has halted or strayed from the right path, it has been, either because its votaries have been content with mere unverified or unverifiable speculation (and this is the commonest case, because observation and experiment are hard work, while speculation is amusing); or it has been, because the accumulation of details of observation has for a time excluded speculation.
Medicine is the science by which we learn the various states of the human body in health and when not in health, and the means by which health is likely to be lost and, when lost, is likely to be restored back to health. In other words, it is the art whereby health is conserved and the art whereby it is restored after being lost. While some divide medicine into a theoretical and a practical [applied] science, others may assume that it is only theoretical because they see it as a pure science. But, in truth, every science has both a theoretical and a practical side.
For the theory-practice iteration to work, the scientist must be, as it were, mentally ambidextrous; fascinated equally on the one hand by possible meanings, theories, and tentative models to be induced from data and the practical reality of the real world, and on the other with the factual implications deducible from tentative theories, models and hypotheses.
There is a distinction, but no opposition, between theory and practice. Each to a certain extent supposes the other. Theory is dependent on practice; practice must have preceded theory.
So far I have been speaking of theoretical science, which is an attempt to understand the world. Practical science, which is an attempt to change the world, has been important from the first, and has continually increased in importance, until it has almost ousted theoretical science from men's thoughts.
As soon as science has emerged from its initial stages, theoretical advances are no longer achieved merely by a process of arrangement. Guided by empirical data, the investigator rather develops a system of thought which, in general, is built up logically from a small number of fundamental assumptions, the so-called axioms. We call such a system of thought a theory. The theory finds the justification for its existence in the fact that it correlates a large number of single observations, and it is just here that the 'truth' of the theory lies.
The word constructionism is a mnemonic for two aspects of the theory of science education underlying this project. From constructivist theories of psychology we take a view of learning as a reconstruction rather than as a transmission of knowledge. Then we extend the idea of manipulative materials to the idea that learning is most effective when part of an activity the learner experiences as constructing a meaningful product.
Tailoring the facts to fit one's theory constitutes neither good science nor good journalism. Rather, it is intellectually dishonest and, when published for consumption by a mass audience, adds up to propaganda.
The Western Idea of practice is to acquire a skill. It is very much related to your work ethic, which enjoins us to endure struggle or boredom now in return for future rewards. The Eastern idea of practice, on the other hand, is to create the person, or rather to actualize or reveal the complete person who is already there.... Not only is practice necessary to art, it is art.
Theory is worth but little, unless it can explain its own phenomena, and it must effect this without contradicting itself; therefore, the facts are sometimes assimilated to the theory, rather than the theory to the facts.
The theory of undirected evolution is already dead, but the work of science continues.
I think that only daring speculation can lead us further and not accumulation of facts.
The fear of speculation, the ostensible rush from the theoretical to the practical, brings about the same shallowness in action that it does in knowledge. It is by studying a strictly theoretical philosophy that we become most acquainted with Ideas, and only Ideas provide action with vigour and ethical meaning.
For science can only ascertain what is, but not what should be, and outside of its domain value judgments of all kinds remain necessary. Religion, on the other hand, deals only with evaluations of human thought and action: it cannot justifiably speak of facts and relationships between facts.
There's always a tension in my world between the pragmatic and the practical and the theoretical. I have a very theoretical turn of mind, but I also like to test things in place.
Without theory, practice is but routine born of habit. Theory alone can bring forth and develop the spirit of invention. ... [Do not] share the opinion of those narrow minds who disdain everything in science which has not an immediate application. ... A theoretical discovery has but the merit of its existence: it awakens hope, and that is all. But let it be cultivated, let it grow, and you will see what it will become.
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