A century ago mainstream science was still quite happy to countenance vital and mental powers which had a 'downwards' causal influence on the physical realm in a straightforwardly interactionist way. It was only in the middle of the last century that science finally concluded that there are no such non-physical forces. At which point a whole pile of smart philosophers (Feigl, Smart, Putnam, Davidson, Lewis) quickly pointed out that mental, biological and social phenomena must themselves be physical, in order to produce the physical effects that they do.