A Quote by Horace Walpole

Serendipitous discoveries are made by chance, found without looking for them but possible only through a sharp vision and sagacity, ready to see the unexpected and never indulgent with the apparently unexplainable.
You know, I've learned that sometimes you can only see what you want to see by changing where you stand. And standing somewhere unexpected can lead to unexpected discoveries.
They consider me to have sharp and penetrating vision because I see them through the mesh of a sieve.
To achieve accurate knowledge of others, if such a thing were possible, we could only ever arrive at it through the slow and unsure recognition of our own initial optical inaccuracies. However, such knowledge is not possible: for, while our vision of others is being adjusted, they, who are not made of mere brute matter, are also changing; we think we have managed to see them more clearly, but they shift; and when we believe we have them fully in focus, it is merely our older images of them that we have clarified, but which are themselves already out of date.
Engineering serendipity is this idea that we can help people come across unexpected but helpful connections at a better than random rate. And in some ways it's based on trying to reassess this notion of serendipitous as lucky - to think of serendipitous as smart.
But medicine has long had all its means to hand, and has discovered both a principle and a method, through which the discoveries made during a long period are many and excellent, while full discovery will be made, if the inquirer be competent, conduct his researches with knowledge of the discoveries already made, and make them his starting-point. But anyone who, casting aside and rejecting all these means, attempts to conduct research in any other way or after another fashion, and asserts that he has found out anything, is and has been victim of deception.
It is notorious that the same discovery is frequently made simultaneously and quite independently, by different persons. Thus, to speak of only a few cases in late years, the discoveries of photography, of electric telegraphy, and of the planet Neptune through theoretical calculations, have all their rival claimants. It would seem, that discoveries are usually made when the time is ripe for them - that is to say, when the ideas from which they naturally flow are fermenting in the minds of many men.
The mind is found most acute and most uneasy in the morning. Uneasiness is, indeed, a species of sagacity - a passive sagacity. Fools are never uneasy.
A man who is seeking for realization is not only going around searching for his spectacles without realizing that they are on his nose all the time, but also were he not actually looking through them he would not be able to see what he is looking for!
Discoveries aren't made by one person exploring by themselves. And discoveries aren't made overnight. People don't see the thousands of hours that go into it.
[In the case of research director, Willis R. Whitney, whose style was to give talented investigators as much freedom as possible, you may define "serendipity" as] the art of profiting from unexpected occurrences. When you do things in that way you get unexpected results. Then you do something else and you get unexpected results in another line, and you do that on a third line and then all of a sudden you see that one of these lines has something to do with the other. Then you make a discovery that you never could have made by going on a direct road.
It is never late to ask yourself “Am I ready to change my life, am I ready to change myself?”. However old we are, whatever we went through, it is always possible to reborn. If each day is a copy of the last one, what a pity! Every breath is a chance to reborn. But to reborn into a new life, you have to die before dying.
Disgust relies on moral obtuseness. It is possible to view another human being as a slimy slug or a piece of revolting trash only if one has never made a serious good-faith attempt to see the world through that person’s eyes or to experience that person’s feelings. Disgust imputes to the other a subhuman nature. How, by contrast, do we ever become able to see one another as human? Only through the exercise of imagination.
It is easy to predict that some of the discoveries of research directed towards Grand Challenges - but only the most unexpected ones, and at the most unexpected times - will be the basis of revolutionary improvements in the way that we exploit the power of our future computing devices.
It is a simple matter to see the obvious, to do the expected. The tendency of the individual life is to be static rather than dynamic, and this tendency is made into a propulsion by civilization, where the obvious only is seen, and the unexpected rarely happens. When the unexpected does happen, however, and when it is of sufficiently grave import, the unfit perish. They do not see what is not obvious, are unable to do the unexpected, are incapable of adjusting their well-grooved lives to other and strange grooves. In short, when they come to the end of their own groove, they die.
Without going outside, you may know the whole world, without looking through the window, you may see the ways of heaven. The farther you go, the less you know. Thus the sage knows without traveling; he sees without looking; he works without doing.
I never made one of my discoveries through the process of rational thinking
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