A Quote by James D. Watson
I would only once have the opportunity to let my scientific career encompass a path from the double helix to the three billion steps of the human genome.
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'Genes, Girls, and Gamow' was an attempt, even more than 'The Double Helix,' to mix science with one's personal life. With 'The Double Helix,' no one had done it before, but I thought I'd try.
My career has been two steps forward and three steps back.
If we could magically transport ourselves back to the young Earth, when it was only a billion years old or two billion years old or three billion years old or four billion years old, we wouldn't be able to survive. We would have a hard time surviving if we were transported to the time when dinosaurs were around.
The first thing you have to do is to sequence the Neanderthal genome, and that has actually been done. The next step would be to chop this genome up into, say, 10,000 chunks and then... assemble all the chunks in a human stem cell, which would enable you to finally create a Neanderthal clone.
The question is, are there useful things that we can do with the results of a genome sequence that would bring benefit? And the answer is, today, should the majority of people go and have their genome sequenced? Probably not. But are there particular circumstances in which genome sequencing is really helpful? Yes, there are.
You can remember it if you want by unraveling the double helix of inner knowing.
If I had been married earlier in life, I wouldn't have seen the double helix. I would have been taking care of the kids on Saturday. On the other hand, I was lonely a lot of the time.
The wealthiest 300 people have greater riches than the three billion poorest. The three wealthiest people have greater riches than the 48 poorest countries put together. With only limited environmental space to accommodate the expected 9 billion human inhabitants of the world by 2050, such disparities in consumption are clearly not sustainable
The mouse genome is an invaluable tool to interpret the human genome.
[Professor Pauling] confesses that he had harboured the feeling that sooner or later he would be the one to get the DNA structure; and although he was pleased with the double-helix, he 'rather wished the idea had been his'.
Consider: The human genome consists of about 3.3 billion base pairs. Since there are only four types of pair, that amounts to 0.8 gigabytes of information, or about what you can fit on a CD. With a microwave radio transmitter, you could beam that amount of information into space in a few minutes, and have it travel to anyone at light speed.
Every time you understand something, religion becomes less likely. Only with the discovery of the double helix and the ensuing genetic revolution have we had grounds for thinking that the powers held traditionally to be the exclusive property of the gods might one day be ours. 5
There are 6.6 billion people on the planet today. With organic farming we could only feed four billion of them. Which two billion would volunteer to die?
In the field one has to face a chaos of facts, some of which are so small that they seem insignificant; others loom so large that they are hard to encompass with one synthetic glance. But in this crude form they are not scientific facts at all; they are absolutely elusive, and can be fixed only by interpretation, by seeing them sub specie aeternitatis, by grasping what is essential in them and fixing this. Only laws and generalizations are scientific facts, and field work consists only and exclusively in the interpretation of the chaotic social reality, in subordinating it to general rules.
There's not a lot of whimsicality in the form, not a lot of indulgence allowed. Like when I was younger, I would sometimes go, "Oh, every other section will be narrated by a chair." Or, "It will be a double helix shape!" That never really worked.
One of the big challenges now is to figure out just how many viruses there really are in the human genome. So far the estimate is 8.3% of our genome is virus, but it actually could be a lot higher.
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