A Quote by James Rothman

I started taking a basic biology course, and I really loved it. I started asking research questions incessantly. I was drawn very quickly to biology. — © James Rothman
I started taking a basic biology course, and I really loved it. I started asking research questions incessantly. I was drawn very quickly to biology.
Evolution, cell biology, biochemistry, and developmental biology have made extraordinary progress in the last hundred years - much of it since I was weaned on schoolboy biology in the 1930s. Most striking of all is the sudden eruption of molecular biology starting in the 1950s.
What's been gratifying is to live long enough to see molecular biology and evolutionary biology growing toward each other and uniting in research efforts.
When I started in the field, aging research was the backwater of biology. The idea that you could find a molecule that would prevent many diseases at once was considered impossible.
If belief in evolution is a requirement to be a real scientist, it’s interesting to consider a quote from Dr. Marc Kirschner, founding chair of the Department of Systems Biology at Harvard Medical School: “In fact, over the last 100 years, almost all of biology has proceeded independent of evolution, except evolutionary biology itself. Molecular biology, biochemistry, physiology, have not taken evolution into account at all.
The language of chemistry simply does not mesh with that of biology. Chemistry is about substances and how they react, whereas biology appeals to concepts such as information and organisation. Informational narratives permeate biology.
Synthetic biology can help address key challenges facing the planet and its population. Research in synthetic biology may lead to new things such as programmed cells that self-assemble at the sites of disease to repair damage.
Biology is far from understanding exactly how a single cell develops into a baby, but research suggests that human development can ultimately be explained in terms of biochemistry and molecular biology. Most scientists would make a similar statement about evolution.
I started asking the big questions that I had asked in college, that my compatriots the Greek philosophers had asked, like 'what is a good life?' Socrates famously said that 'The unexamined life is not worth living.' I started asking these questions from the starting point of 'what is success?'
It is now widely realized that nearly all the 'classical' problems of molecular biology have either been solved or will be solved in the next decade. The entry of large numbers of American and other biochemists into the field will ensure that all the chemical details of replication and transcription will be elucidated. Because of this, I have long felt that the future of molecular biology lies in the extension of research to other fields of biology, notably development and the nervous system.
I never challenged control of the band. Basically, all I did was start asking questions. There's an old adage in Hollywood amongst managers: 'Pay your acts enough money that they don't ask questions.' And I started asking questions.
I started working on ribosomes when I was a post doc, in 1978, when it would have been impossible, really, to solve it. But, it was just a fundamental problem in biology.
Let's admit that feminism came from liberalism and it was very positive. But then it went dark. It went into a bad place. When feminism replaced biology with social construct, they started to say that everything about a human being was created by your environment or by your - by environmental cues as opposed to innate traits... Like you didn't achieve what you could get because it was your fault. They denied traits that are applied across all cultures. And that's where feminism went wrong is it denied biology and makes them look foolish.
Scientific practice is above all a story-telling practice. ... Biology is inherently historical, and its form of discourse is inherently narrative. ... Biology as a way of knowing the world is kin to Romantic literature, with its discourse about organic form and function. Biology is the fiction appropriate to objects called organisms; biology fashions the facts "discovered" about organic beings.
I stopped asking myself questions like what the value of my stock was and started asking more fundamental questions of life and death.
I was drawn to biology and history and, of course, art. And I loved languages. The biggest problem I had is that I wasn't taught about the connections between all these things. I think that would have given life a lot more meaning and it would be a lot more enjoyable.
It will be in the convergence of evolutionary biology, developmental biology and cancer biology that the answer to cancer will lie. Nor will this confluence be a one-way street.
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