A Quote by John Gurdon

The aim of a nuclear-transplant experiment is to insert the nucleus of a specialized cell into an unfertilized egg whose nucleus has been removed. — © John Gurdon
The aim of a nuclear-transplant experiment is to insert the nucleus of a specialized cell into an unfertilized egg whose nucleus has been removed.
Within one year of starting work, I had found that the nucleus of an endoderm cell from an advanced tadpole was able to yield some normal development up to the nuclear transplant tadpole stage.
In principle. what is done is to take the nucleus out of a cell with a very fine micro-pipette or needle and introduce it into an egg. That had been done with amphibians a long time ago, and then there was a long pause of many years before people were clever enough to make that work in the sheep.
For it is not cell nuclei, not even individual chromosomes, but certain parts of certain chromosomes from certain cells that must be isolated and collected in enormous quantities for analysis; that would be the precondition for placing the chemist in such a position as would allow him to analyse [the hereditary material] more minutely than [can] the morphologists ... For the morphology of the nucleus has reference at the very least to the gearing of the clock, but at best the chemistry of the nucleus refers only to the metal from which the gears are formed.
When you create a nucleus of activity and it starts gaining steam, what you want to do in business is you want to create as many streams or legs out of that nucleus as possible.
First the stalk — then the roots. First the need — then the means to satisfy that need . First the nucleus — then the elements needed for its growth. The seed is a primary cause. The need, the nucleus, both are primary causes. Conditions — they are secondary. Given enough life in the nucleus, it will draw to itself the necessary means for growth regardless of conditions.
A cell is a complex structure, with its investing membrane, nucleus, and nucleolus.
Nuclear transplantation is a technique that has enormously facilitated the analysis of these interactions between nucleus and cytoplasm.
Atoms have a nucleus, made of protons and neutrons bound together. Around this nucleus shells of electrons spin, and each shell is either full or trying to get full, to balance with the number of protons-to balance the number of positive and negative charges. An atom is like a human heart, you see.
We [Frisch and Lise Meitner] walked up and down in the snow, I on skis and she on foot (she said and proved that she could get along just as fast that way), and gradually the idea took shape that this was no chipping or cracking of the nucleus but rather a process to be explained by Bohr's idea that the nucleus was like a liquid drop; such a drop might elongate and divide itself.
Despite their differences, pride, shame, and guilt all activate similar neural circuits, including the dorsomedial prefrontal cortex, amygdala, insula, and the nucleus accumbens. Interestingly, pride is the most powerful of these emotions at triggering activity in these regions - except in the nucleus accumbens, where guilt and shame win out. This explains why it can be so appealing to heap guilt and shame on ourselves - they're activating the brain's reward center.
I think there's a reason to go off and do something and experiment - splinter off and do something different. It keeps the nucleus of Fleetwood Mac fresh.
The more the relationships of the nitrogen-rich substances to the cell nucleus were recognized, the more the question of the arrangement of the nitrogen and carbon atoms in the molecule came to stand out.
Atoms consist of a positive nucleus and negative electrons flying around outside it. Electrons closest to the nucleus feel a strong negative-on-positive tug, and the bigger atoms get, the bigger the tug. In really big atoms, electrons whip around at speeds close to the speed of light.
A woman's chastity consists, like an onion, of a series of coats. You may strip off the outer ones without doing much mischief, perhaps none at all ; but you keep taking off one after another, in expectation of coming to the inner nucleus, including the whole value of the matter. It proves, however, that there is no such nucleus, and that chastity is diffused through the whole series of coats, is lessened with the removal of each, and vanishes with the final one which you supposed would introduce you to the hidden pearl.
The importance of the egg's non-nuclear material - the cytoplasm - in early development is apparent in the consistent relation that is seen to exist between certain regions in the cytoplasm of a fertilized egg and certain kinds or directions of cell differentiation.
If one stretches out the DNA contained in the nucleus of a human cell, one obtains a two-yard-long thread that is only ten atoms wide. This thread is a billion times longer than its own width. Relatively speaking, it is as if your little finger stretched from Paris to Los Angeles.
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