A Quote by John Stuart Mill

It appears, then, to be a condition of a genuinely scientific hypothesis, that it be not destined always to remain an hypothesis, but be certain to be either proved or disproved by.. .comparison with observed facts.
[Coining phrase "null hypothesis"] In relation to any experiment we may speak of this hypothesis as the "null hypothesis," and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.
The scientific discovery appears first as the hypothesis of an analogy; and science tends to become independent of the hypothesis.
But I should be very sorry if an interpretation founded on a most conjectural scientific hypothesis were to get fastened to the text in Genesis... The rate of change of scientific hypothesis is naturally much more rapid than that of Biblical interpretations, so that if an interpretation is founded on such an hypothesis, it may help to keep the hypothesis above ground long after it ought to be buried and forgotten.
Hypothesis is a toll which can cause trouble if not used properly. We must be ready to abandon our hypothesis as soon as it is shown to be inconsistent with the facts.
The first objection to Darwinism is that it is only a guess and was never anything more. It is called a "hypothesis," but the word "hypothesis," though euphonious, dignified and high-sounding, is merely a scientific synonym for the old-fashioned word "guess." If Darwin had advanced his views as a guess they would not have survived for a year, but they have floated for half a century, buoyed up by the inflated word "hypothesis." When it is understood that "hypothesis" means "guess," people will inspect it more carefully before accepting it.
If we consistently act on the optimistic hypothesis, this hypothesis will tend to be realised; whilst by acting on the pessimistic hypothesis we can keep ourselves for ever in the pit of want.
A hypothesis is empirical or scientific only if it can be tested by experience. A hypothesis or theory which cannot be, at least in principle, falsified by empirical observations and experiments does not belong to the realm of science.
Mr. Darwin's hypothesis is not, so far as I am aware, inconsistent with any known biological fact; on the contrary, if admitted, the facts of Development, of Comparative Anatomy, of Geographical Distribution, and of Palaeontology, become connected together, and exhibit a meaning such as they never possessed before; and I, for one, am fully convinced that if not precisely true, that hypothesis is as near an approximation to the truth as, for example, the Copernican hypothesis was to the true theory of the planetary motions.
The rules of scientific investigation always require us, when we enter the domains of conjecture, to adopt that hypothesis by which the greatest number of known facts and phenomena may be reconciled.
Tormented by conflicting feelings, I appealed to reason ; and it is reason which, amid so many dogmatic contradictions, now forces the hypothesis upon me. A priori dogmatism, applying itself to God, has proved fruitless: who knows whither the hypothesis, in its turn, will lead us? I will explain therefore how, studying in the silence of my heart, and far from every human consideration, the mystery of social revolutions, God, the great unknown, has become for me an hypothesis, I mean a necessary dialectical tool.
Making an investment decision is like formulating a scientific hypothesis and submitting it to a practical test. The main difference is that the hypothesis that underlies an investment decision is intended to make money and not to establish a universally valid generalization.
However the machine would permit us to test the hypothesis for any special value of n. We could carry out such tests for a sequence of consecutive values n=2,3,.. up to, say, n=100. If the result of at least one test were negative, the hypothesis would prove to be false; otherwise our confidence in the hypothesis would increase, and we should feel encouraged to attempt establishing the hypothesis, instead of trying to construct a counterexample.
The Gaia Hypothesis of James Lovelock [and Lynn Margulis] puts forward a scientific view of the living Earth, which in one respect is modern, empherical, scientific, in another respect re-awakens an ancient archetype, which in fact is so clearly suggested by the very name of the hypothesis, Gaia, the Greek name for Mother Earth.
If the hypothesis of evolution is true, living matter must have arisen from non-living matter; for by the hypothesis the condition of the globe was at one time such, that living matter could not have existed in it, life being entirely incompatible with the gaseous state.
A hypothesis is something which looks as if it might be true and were true, and which is capable of verification or refutation by comparison with facts.
Current organisms have a higher probability of sharing a single code if the common ancestry hypothesis is true than they'd have if the hypothesis of separate ancestry were true. That is, the simpler hypothesis has the higher likelihood in the technical sense of "likelihood" used in statistics.
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