A Quote by Karl Popper

The growth of our knowledge is the result of a process closely resembling what Darwin called 'natural selection'; that is, the natural selection of hypotheses: our knowledge consists, at every moment, of those hypotheses which have shown their (comparative) fitness by surviving so far in their struggle for existence, a competitive struggle which eliminates those hypotheses which are unfit.
Darwin repeatedly used the hypothesis of common ancestry as a platform on which to build his various ideas about testing hypotheses concerning natural selection. He also argued that adaptive similarities provide little or no evidence for common ancestry. Although this second claim needs to be fine-tuned, Darwin was right that ample evidence for common ancestry can exist even if none of the characteristics we observe were caused to evolve by natural selection.
Creationists argue that natural selection is only a negative process, and therefore cannot create anything. Chopra argues that skepticism is only a negative process, and therefore does not lead to knowledge. Both are wrong for the same reasons. They ignore the generation of diversity and new ideas upon which natural selection and skepticism acts. Weeding out the unfit is critical to both - natural selection allows evolution to proceed, and skepticism allows science to advance.
This survival of the fittest which I have here sought to express in mechanical terms, is that which Mr. Darwin has called "natural selection", or the preservation of favoured races in the struggle for life.
Certainly it is permitted to anyone to put forward whatever hypotheses he wishes, and to develop the logical consequences contained in those hypotheses. But in order that this work merit the name of Geometry, it is necessary that these hypotheses or postulates express the result of the more simple and elementary observations of physical figures.
Now let me step back from the problem and very generally discuss natural selection and what we know about it. I think it is safe to say that we know for sure that natural selection, as a process, does work. There is a mountain of experimental and observational evidence, much of it predating genetics, which shows that natural selection as a biological process works.
Given any rule, however "fundamental" or "necessary" for science, there are always circumstances when it is advisable not only to ignore the rule, but to adopt its opposite. For example, there are circumstances when it is advisable to introduce, elaborate and defend ad hoc hypotheses, or hypotheses which contradict well-established and generally accepted experimental results, or hypotheses whose content is smaller than the content of the existing and empirically adequate alternative, or self-inconsistent hypotheses, and so on.
The knowledge of Natural-History, being Observation of Matters of Fact, is more certain than most others, and in my slender Opinion, less subject to Mistakes than Reasonings, Hypotheses, and Deductions are; ... These are things we are sure of, so far as our Senses are not fallible; and which, in probability, have been ever since the Creation, and will remain to the End of the World, in the same Condition we now find them.
The hypotheses we accept ought to explain phenomena which we have observed. But they ought to do more than this: our hypotheses ought to foretell phenomena which have not yet been observed.
The hypotheses which we accept ought to explain phenomena which we have observed. But they ought to do more than this; our hypotheses ought to foretell phenomena which have not yet been observed; ... because if the rule prevails, it includes all cases; and will determine them all, if we can only calculate its real consequences. Hence it will predict the results of new combinations, as well as explain the appearances which have occurred in old ones. And that it does this with certainty and correctness, is one mode in which the hypothesis is to be verified as right and useful.
Natural Selection is not Evolution. Yet, ever since the two words have been in common use, the theory of Natural Selection has been employed as a convenient abbreviation for the theory of Evolution by means of Natural Selection, put forward by Darwin and Wallace. This has had the unfortunate consequence that the theory of Natural Selection itself has scarcely ever, if ever, received separate consideration.
Are not all Hypotheses erroneous, in which Light is supposed to consist in Pression or Motion, propagated through a fluid Medium? For in all these Hypotheses the Phaenomena of Light have been hitherto explain'd by supposing that they arise from new Modifications of the Rays; which is an erroneous Supposition.
The Lean Startup is a process for turning ideas into commercial ventures. Its premise is that startups begin with a series of untested hypotheses. They succeed by getting out of the building, testing those hypotheses and learning by iterating and refining minimal viable products in front of potential customers.
The Lean Startup process builds new ventures more efficiently. It has three parts: a business model canvas to frame hypotheses, customer development to get out of the building to test those hypotheses, and agile engineering to build minimum viable products.
Quantitative work shows clearly that natural selection is a reality, and that, among other things, it selects Mendelian genes, which are known to be distributed at random through wild populations, and to follow the laws of chance in their distribution to offspring. In other words, they are an agency producing variation of the kind which Darwin postulated as the raw material on which selection acts.
I have not been able to discover the cause of those properties of gravity from phenomena, and I frame no hypotheses; for whatever is not deduced from the phenomena is to be called a hypothesis, and hypotheses, whether metaphysical or physical, whether of occult qualities or mechanical, have no place in experimental philosophy.
The slow, the never ending approach to truth consists in perpetually forming and testing hypotheses, accepting those at which at the time seem to fit the facts and rejecting the others.
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