A Quote by Laurie Glimcher

Cancer can no longer be classified according to the organ in which it arises. It has to be characterized in terms of the genetic mutation that exists. — © Laurie Glimcher
Cancer can no longer be classified according to the organ in which it arises. It has to be characterized in terms of the genetic mutation that exists.
A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms of its internal genetic anatomy has really changed the way we treat and approach cancer in general.
Every single cancer is a genetic disease. Not necessarily inherited from your parents, but it's genetic changes which cause cancer. So as we sequence the genomes of tumours and compare those to the sequence of patients, we're getting down to the fundamental basis of each individual person's cancer.
Although not yet routine, many cancer centers have the technology to sequence some or all of a patient's cancer genome. This can provide massive amounts of valuable information about your cancer, including whether you have genetic mutations and other abnormalities for which new drugs are available.
Part of the problem with the discovery of the so-called breast-cancer genes was that physicians wrongly told women that had the genetic changes associated with the genes that they had a 99% chance of getting breast cancer. Turns out all women that have these genetic changes don't get breast cancer.
On the morning of May 1, 2018, I woke up knowing that the day I had anticipated for nine years had finally arrived. It was the day of my preventative double mastectomy - the day I would attack my BRCA 2 genetic mutation head-on and take my chances of breast cancer from 84 percent to virtually zero.
Say you have cancer - you have this broad thing we call cancer; we're going to irradiate you and pump this poisonous material into you and hope more of the bad stuff dies than the good. That is going to seem so medieval when we can fix it on a genetic level, and Foundation Medicine is the first step to diagnosing it on a genetic level.
Every mutation through a new combination of genetic factors that provides the organism with a new opportunity for coming to terms with the conditions of its environment signifies no more and no less than that new information about this environment has got into that organic system. Adaptation is essentially a cognitive process.
Having the BRCA mutation significantly increases the risk of breast cancer, but it is not always the only factor. Lifestyle choices may increase or decrease the risk of breast cancer, but that knowledge is an opportunity to empower ourselves, not to blame.
The food you eat is among the most significant factors affecting your genes and pushing them toward cancer by causing mutation or disruption in their function. That is, what you eat can either prevent cancer and other chronic illnesses or help cause them.
If you ever meet a guy and you fall in love with him, but because of some weird genetic mutation he doesn't seem to return the feeling?... Wear that dress.
Throughout the book, she refers to herself as "the side effect," which is just totally correct. Cancer kids are essentially side effects of the relentless mutation that made the diversity of life on earth possible.
In my practice, the majority of mutation carriers choose mastectomy; however, for those without cancer, they have much more control over the timing. For younger women, we might wait until they have found a life partner, or until after childbearing. Older women who find out they carry a mutation have unwittingly escaped a large percentage of their risk, and therefore, the calculated future risk is not necessarily a daunting number.
I have that gene mutation too and it’s not something I would believe in for myself. I wouldn’t call it the brave choice. I actually think it’s the most fearful choice you can make when confronting anything with cancer. My belief is that cancer comes from inside you and so much of it has to do with the environment of your body. It’s the stress that will turn that gene on or not.
Only cells that had been transformed by a virus or a genetic mutation had the potential to become immortal.
The organizing principle, which according to an eternal law creates the different essential organs of the body, and animates them, is not itself seated in one particular organ.
Only a very small number of the e-mails containing classified information bore markings indicating the presence of classified information. But even if information is not marked 'classified' in an e-mail, participants who know or should know that the subject matter is classified are still obligated to protect it.
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