A Quote by Ludwig von Mises

Scientific research sooner or later, but inevitably, encounters something ultimately given that it cannot trace back to something else of which it would appear as the regular or necessary derivative. Scientific progress consists in pushing further back this ultimately given.
The great scientific achievements are research programmes which can be evaluated in terms of progressive and degenerative problemshifts; and scientific revolutions consist of one research programme superceding (overtaking in progress) another. This methodology offers a new rational reconstruction of science.
vivisection is not the same thing as scientific progress. There is such a thing as scientific progress. But this wholesale dedication of scientists to vivisection, which is the easy and cheap way, actually prevents them from scientific progress, for true progress is difficult and requires genius and imagination in its devoted workers.
The scientist is not much given to talking of the riddle of the universe. "Riddle" is not a scientific term. The conception of a riddle is "something which can he solved." And hence the scientist does not use that popular phrase. We don't know the why of anything. On that matter we are no further advanced than was the cavedweller. The scientist is contented if he can contribute something toward the knowledge of what is and how it is.
Later scientific theories are better than earlier ones for solving puzzles in the often quite different environments to which they are applied. That is not a relativist's position, and it displays the sense in which I am a convinced believer in scientific progress.
First, inevitably, the idea, the fantasy, the fairy tale. Then, scientific calculation. Ultimately, fulfillment crowns the dream.
Remember that [scientific thought] is the guide of action; that the truth which it arrives at is not that which we can ideally contemplate without error, but that which we may act upon without fear; and you cannot fail to see that scientific thought is not an accompaniment or condition of human progress, but human progress itself.
You do what you do - in the circumstances in which you find yourself - because of the way you are. So if you're going to be ultimately responsible for what you do, you're going to have to be ultimately responsible for the way you are - at least in certain mental respects. But you can't be ultimately responsible for the way you are (for the reasons just given). So you can't be ultimately responsible for what you do.
As time passed I became an avid reader of popular scientific books, wanting to know as much as I could about the world in which I lived. Gradually I began to see a pattern of nonsense in much scientific writing. Scientific explanations given regarding the origins or functioning of various phenomena simply didn't make sense.
The technological overflow from scientific research has brought scientific research this bad name about carrying an irresponsibility and an alienation from God - because scientific research has led to things like the atom bomb, it's led to problems with depletion of ozone in the Earth's atmosphere, or at least it's revealed those problems.
Is it necessary to practice all these asanas, further and further? Is it necessary to develop scientific researches further and further? To a yogi, the body is a laboratory, a field of experiments and perpetual researches.
First love is unrequited ultimately because it’s so huge.It’s such an act of giving and it requires so much back that it can never be given back. It’s like an atom bomb. It’s like… It’s all the energy of who you are and who you want to be and what you love and what you hope to be explodes. It is impossible for a single... human being to offer that back to you in a mutual way.
"Normal science" means research firmly based upon one or more past scientific achievements, achievements that some particular scientific community acknowledges for a time as supplying the foundation for its further practice.
Moreover, only a strong and united scientific opinion imposing the intrinsic value of scientific progress on society at large can elicit the support of scientific inquiry by the general public.
The only thing that is unqualifiedly given is the total pervasive quality; and the objection to calling it "given" is that the word suggests something to which it is given, mind or thought or consciousness or whatever, as well possibly as something that gives.
A religious creed differs from a scientific theory in claiming to embody eternal and absolutely certain truth, whereas science is always tentative, expecting that modification in its present theories will sooner or later be found necessary, and aware that its method is one which is logically incapable of arriving at a complete and final demonstration.
Given cognitive vulnerabilities, it would be convenient to have an arrangement whereby reality could tell us off; and that is precisely what science is. Scientific methodology is the arrangement that allows reality to answer us back.
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