A Quote by Martin Chalfie

For a decade, I had been studying a transparent worm, the C. elegans. I immediately thought, if you could put the G.F.P. gene into C. elegans, you'd then be able to see biological processes in live animals. Until then, we had to kill them and prepare their tissues chemically to visualize proteins or active genes within cells.

Martin Chalfie

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Able Active Animals Been Biological Cells Could Decade Gene Genes Had Immediately Live Prepare Processes Proteins Put See Studying Them Then Thought Tissues Transparent Until Visualize Within Worm

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Martin Chalfie
American - Scientist
Born: January 15, 1947

One of the great things about working on C. elegans was the fact that it was transparent, and so when I first heard that seminar describing GFP, and realised, 'I work on this transparent animal, this is going to be terrific! I'll be able to see the cells within the living animal.'

Martin Chalfie

Our work on C. elegans emphasized the benefits of sharing large amounts of information. We took a global approach to discover the mechanisms that led to the development of the worm.

John Sulston

Traditional academic science describes human beings as highly developed animals and biological thinking machines. We appear to be Newtonian objects made of atoms, molecules, cells, tissues, and organs.

Stanislav Grof

Something that had been a single cell, a cluster of cells, a little sac of tissue, a kind of worm, a potential fish with gills, stirred in her womb and would one day become a man--a grown man, suffering and enjoying, loving and hating, thinking, remembering, imagining. And what had been a blob of jelly within her body would invent a god and worship; what had been a kind of fish would create, and, having created, would become the battleground of disputing good and evil; what had blindly lived in her as a parasitic worm would look at the stars, would listen to music, would read poetry.

Aldous Huxley

We know cancer is caused ultimately via a link between the environment and genes. There are genes inside cells that tell cells to grow and the same genes tell cells to stop growing. When you deregulate these genes, you unleash cancer. Now, what disrupts these genes? Mutations.

Siddhartha Mukherjee

Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to genes have bigger consequences: They can disable proteins and kill a creature.

Sam Kean

It turns out that the very genes that turn on in cancer cells perform vital functions in normal cells. In other words, the very genes that allow our embryos to grow or our brains to grow, our bodies to grow, if you mutate them, if you distort them, then you unleash cancer.

Siddhartha Mukherjee

Up until then it had only been himself. Up to then it had been a private wrestle between him and himself. Nobody else much entered into it. After the people came into it he was, of course, a different man. Everything had changed then and he was no longer the virgin, with the virgin's right to insist upon platonic love. Life, in time, takes every maidenhead, even if it has to dry it up; it does not matter how the owner wants to keep it. Up to then he had been the young idealist. But he could not stay there. Not after the other people entered into it.

James Jones

I recognized him then; that is, I finally comprehended what I had known but had never been able to formulate: he had always been complete. He had finished the work of becoming himself, long before any of us could even imagine such a feat was possible.

Aleksandar Hemon

I wasn't afraid of anything until I had a kid. Then I was terrified because immediately I could imagine a hundred ways in which I could not protect him.

John Irving

Each memory was brought to life before me and within me. I could not avoid them. Neither could I rationalize, explain away. I could only re-experience with total cognizance, unprotected by pretense. Self delusion was impossible, truth exposed in this blinding light. Nothing as I thought it had been. Nothing as I hoped it had been. Only as it had been.

Richard Matheson

A lot of the musicians asked me if when I hit my high-Cs on the records I had a clarinet take the notes. Some [thought] I had invented some kind of gadget so I could play high register. They weren't satisfied until they handed me a trumpet that they had with them and had me swing it. Then they cheered.

Louis Armstrong

If all the animals and man had been evolved in this ascendant manner, then there had been no first parents, no Eden, and no Fall. And if there had been no fall, then the entire historical fabric of Christianity, the story of the first sin and the reason for an atonement ... collapsed like a house of cards.

H. G. Wells

Genes are effectively one-dimensional. If you write down the sequence of A, C, G and T, that's kind of what you need to know about that gene. But proteins are three-dimensional. They have to be because we are three-dimensional, and we're made of those proteins. Otherwise we'd all sort of be linear, unimaginably weird creatures.

Francis Collins

There was a man that hated his footprints and his shadow, so one day he thought that if he ran fast enough, his footprints and shadow would not be able to follow him and then he never ever had to look at them again. He ran and he ran as fast as he could, but the shadow and the footprints had no problems keeping up to him. And he ran even faster and all of a sudden he fell dead to the ground. But if he been standing still there hadn't been any footprints and if he had been resting under a tree his shadow had been swallowed of the trees shadow.

Benjamin Hoff

I had a liver transplant, then I had a pacemaker put in, then I had a new knee put it, then I had a heart valve put in. I'm almost brand new. I have a lot of new parts.

Jim Nabors

A Quote by Martin Chalfie

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