A Quote by Martin Chalfie

We have found that fusions of GFP with the RING finger domains of certain E3 ubiquitin ligases creates an unstable GFP. We have used unstable GFP to learn how disruption of microtubules in the touch receptor neurons causes a generalized reduction in protein levels in the cells.
One of the great things about working on C. elegans was the fact that it was transparent, and so when I first heard that seminar describing GFP, and realised, 'I work on this transparent animal, this is going to be terrific! I'll be able to see the cells within the living animal.'
I do think of this prize as the GFP prize, and I happen to fortunately be one of the people that goes along for the ride.
Different cats don't like certain litter. They also don't like an unstable floor, no animal like's unstable floor. So if you put a thin piece of plastic down under a litter box and the cat walks on it and starts to slip, they don't like that. Any animal doesn't like an unstable floor.
I got so used to being unstable that I started to only be comfortable being unstable.
A double minded man is unstable in all his ways. Are you unstable about your relationship to Christ?
If Egypt is unstable, then the entire region is unstable.
There is the old catch-22 line that a mentally unstable person can't know, as per their illness, that they are unstable. But that was wrong. You can and do have the insight to see your own crazy.
There are billions of neurons in our brains, but what are neurons? Just cells. The brain has no knowledge until connections are made between neurons. All that we know, all that we are, comes from the way our neurons are connected.
Receptor chemistry, the chemistry of artificial receptor molecules, may be considered a generalized coordination chemistry, not limited to transition metal ions but extending to all types of substrates: cationic, anionic or neutral species of organic, inorganic or biological nature.
Every thought, feeling, and emotion creates a molecule known as a neuropeptide. Neuropeptides travel throughout your body and hook onto receptor sites of cells and neurons. Your brain takes in the information, converts it into chemicals, and lets your whole body know if there's trouble in the world or cause for celebration. Your body is directly influenced as these molecules course through the bloodstream, delivering the energetic effect of whatever your brain is thinking and feeling.
We're the only species who follow unstable leaders. This is true - it has little to do with America - around the world, pack leaders are unstable. Animals don't follow that.
Being raised in an unstable household makes you understand that the world doesn't exist to accommodate you, which... is something a lot of people struggle to understand well into their adulthood. It makes you realize how quickly a situation can shift, how danger really is everywhere. But crises when the occur, do not catch you off guard; you have never believed you lived under a shelter of some essential benevolence. And an unstable childhood makes you appreciate calmness and not crave excitement.
The North Korean regime is extremely fiery, extremely insecure, sometimes hysterical. And when you're around somebody who's screaming and unstable, the last thing you want to do is add to the instability with your own unstable, hysterical rhetoric.
If you can adapt to and balance in a world that is always moving and unstable, you learn how to become tolerant to the permanence of change and difference.
I work with the president and speak with him multiple times a week. This is a man, he didn't become the president by accident. And as much as everyone wants to talk about stability, was he unstable when he passed the tax reform? Was he unstable when we finally hit back at Syria and said no more chemical weapons?
The precariat consists of a growing proportion of our total society. It is being habituated to accept a life of unstable labour and unstable living. Often they're unable to say what their occupation is, because what they're doing now might be quite different from what they were doing three months ago.
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