A Quote by Nicholas A. Christakis
Realizing the ways in which we humans may have been inadvertently changing our genes for millennia provides a way for us to begin to think about the inevitable genetic revolution in medicine that is going to allow us to advertently change our genes over centuries and even decades.
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Charles Darwin and I and you broke off from the family tree from chimpanzees about five million years ago. They're still our closest genetic kin. We share 98.8 percent of the genes. We share more genes with them than zebras do with horses. And we're also their closest cousin. They have more genetic relation to us than to gorillas.
Epigenetics doesn't change the genetic code, it changes how that's read. Perfectly normal genes can result in cancer or death. Vice-versa, in the right environment, mutant genes won't be expressed. Genes are equivalent to blueprints; epigenetics is the contractor. They change the assembly, the structure.
Recently, results of the Human Genome Project have shattered one of Science's fundamental core beliefs, the concept of genetic determinism. We have been led to believe that our genes determine the character of our lives, yet new research surprisingly reveals that it is the character of our lives that controls our genes. Rather than being victims of our heredity, we are actually masters of our genome.
Is he a dread genetic determinist, or a dread environmental determinist? He is neither, of course, for both these species of bogeyman are as mythical as werewolves. By increasing the information we have about the various causes of the constraints that limit our current opportunities, he has increased our powers to avoid what we want to avoid, prevent what we want to prevent. Knowledge of the roles of our genes, and the genes of the other species around us, is not the enemy of human freedom, but one of its best friends.
Individuals are not stable things, they are fleeting. Chromosomes too are shuffled into oblivion, like hands of cards soon after they are dealt. But the cards themselves survive the shuffling. The cards are the genes. The genes are not destroyed by crossing-over, they merely change partners and march on. Of course they march on. That is their business. They are the replicators and we are their survival machines. When we have served our purpose we are cast aside. But genes are denizens of geological time: genes are forever.
It's a very complex network of genes making products which go into the nucleus and turn on other genes. And, in fact, you find a continuing network of processes going on in a very complex way by which genes are subject to these continual adjustments, as you might say - the computer programmer deciding which genes ultimately will work.
Everyone recognises that genes are part of the story but autism isn't 100% genetic. Even if you have identical twins who share all their genes, you can find that one has autism and one doesn't. That means that there must be some non-genetic factors.
The implication is that this basic idea we have that we are controlled by our genes is false. It's an idea that turns us into victims. I'm saying we are the creators of our situation. The genes are merely the blueprints. We are the contractors, and we can adjust those blueprints. And we can even rewrite them.
And if you listen to Irish music, they say that kilts came from the middle east. So really I'm an Arab. If you listen to the way someone like Sinead O'Connor sang. It could be Muslim. You know that angst that sort of ****. That wail. I think it's in our genes. I think certain stuff is in our genes, like nobody can dance like a black guy. It's in their genes. So we don't have oil, but we have poetry.
Natural species are the library from which genetic engineers can work. Genetic engineers don't make new genes, they rearrange existing ones. Speaking as World Wildlife Fund Executive Vice President, stating the need to conserve biodiversity, even plants and animals having no immediate use, as a unique repository of genes for possible future biogengineering applications.
If, as the dowager had said, we are nothing but gene carriers, why do so many of us have to lead such strangely shaped lives? Wouldn't our genetic purpose-to transmit DNA-be served just as well if we lived simple lives, not bothering our heads with a lot of extraneous thoughts, devoted entirely to preserving life and procreating? Did it benefit the genes in any way for us to lead such intricately warped, even bizarre, lives?
People think if you have deciphered the genome of humans that you can change everything. But you cannot change everything, because you do not know what the genes mean, and you have no methods for changing them, and you can't do experiments with humans like you can with animals.
We share half our genes with the banana. [After the announcement Jun 2000 that a working draft of the genetic sequence of humans had been completed by the Human Genome Project.]
Our experience in fooling around with the genes of mice has taught us that many of the traits that interest us are not definite products of specific mutations but emergent phenomena arising from extremely complex interactions between genes, environment, and life experience.
About 1.2% of the human genome is made up of genes, things that encode for proteins, the stuff that we consider us. There is about 8.3% that's a virus. In other words we're probably about seven times more virus than we are human genes, which is kind of a weird way to thinking about yourself.
Yes, genes are important for understanding our behavior. Incredibly important - after all, they code for every protein pertinent to brain function, endocrinology, etc., etc. But the regulation of genes is often more interesting than the genes themselves, and it's the environment that regulates genes.
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