A Quote by Norman Macbeth

After observing mutations in fruit flies for many years, Professes Goldschmidt fell into despair. The changes, he lamented, were so hopelessly micro [insignificant] that if a thousand mutations were combined in one specimen, there would still be no new species.
We add that it would be all too easy to object that mutations have no evolutionary effect because they are eliminated by natural selection. Lethal mutations (the worst kind) are effectively eliminated, but others persist as alleles. ...Mutants are present within every population, from bacteria to man. There can be no doubt about it. But for the evolutionist, the essential lies elsewhere: in the fact that mutations do not coincide with evolution.
The accumulation of genetic mutations were touted to be enough to change one species to another….No. It wasn’t dishonesty. I think it was wish fulfillment and social momentum. Assumptions, made but not verified, were taught as fact.
Although random mutations influenced the course of evolution, their influence was mainly by loss, alteration, and refinement... Never, however, did that one mutation make a wing, a fruit, a woody stem, or a claw appear. Mutations, in summary, tend to induce sickness, death, or deficiencies. No evidence in the vast literature of heredity changes shows unambiguous evidence that random mutation itself, even with geographical isolation of populations, leads to speciation.
In agriculture, people have taken wild plants that can't be eaten by people - and turned them into wonderful food sources. And that's because genomes can change, and people working with plants have picked mutations. Mutations are nothing more than genetic changes.
Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to genes have bigger consequences: They can disable proteins and kill a creature.
All human beings are, in fact, born with dozens of mutations their parents lacked, and a few of those mutations could well be lethal if we didn't have two copies of every gene, so one can pick up the slack if the other malfunctions.
When you get sick with the flu you get infected with flu viruses and they make lots of new flu viruses, but those new viruses are not exact copies of the old ones. They have mutations in them. A lot of those mutations are harmful.
It takes a huge effort to free yourself from memory, but when you succeed, you start to realize that you’re capable of far more than you imagined. You live in this vast body called the Universe, which contains all the solutions and all the problems. Visit your soul; don’t visit your past. The Universe goes through many mutations and carries the past with it. We call each of those mutations a ‘life,’ but just as the cells in your body change and yet you remain the same, so time does not pass, it merely changes.
Somewhere in our DNA must lie the key mutation (or, more probably, mutations) that set us apart—the mutations that make us the sort of creature that could wipe out its nearest relative, then dig up its bones and reassemble its genome.
Yes, I spent two long years, traveling all over the United States, all over Europe, interviewing many, many, many people who had been thrown out of their academic jobs because they taught that there was a possibility of life coming from something other than Darwinism, who thought that possibly random selection and mutations didn't account for the universe, didn't account for gravity, didn't account for why nobody had ever seen an individual species evolve - no one's ever seen an individual species evolve!
In the meantime, the educated public continues to believe that Darwin has provided all the relevant answers by the magic formula of random mutations plus natural selection -quite unaware of the fact that random mutations turned out to be irrelevant and natural selection tautology.
Clearly, we are a species that is well connected to other species. Whether or not we evolve from them, we are certainly very closely related to them. A series of mutations could change us into all kinds of intermediate species. Whether or not those intermediate species are provably in the past, they could easily be in our future.
I was taught over and over again that the accumulation of random mutations led to evolutionary change - led to new species. I believed it until I looked for evidence.
Millions of Americans would still despair in the eight long years of the Depression that lay ahead and many of their individual dreams would be dashed on the rocks of economic hardship. But collectively, the country was in a new place, with a new confidence that the federal government would actively try to solve problems rather than fiddle or cater to the rich. Hope was no longer for Pollyannas; the cynics about the American system were in retreat.
Cartoons are like fruit flies. Biologists use fruit flies because their large chromosomes and short life cycle make them ideal for studying hereditary changes.
Fundamentalism in most of its forms is the active creation of antibodies to some threatening [god] virus. As long as threatening religions or mutations [heresies] are present, fundamentalism will churn out antibodies to keep the population under control and prevent mutations from getting out of hand.
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