A Quote by Pierre-Joseph Proudhon

Tormented by conflicting feelings, I appealed to reason ; and it is reason which, amid so many dogmatic contradictions, now forces the hypothesis upon me. A priori dogmatism, applying itself to God, has proved fruitless: who knows whither the hypothesis, in its turn, will lead us? I will explain therefore how, studying in the silence of my heart, and far from every human consideration, the mystery of social revolutions, God, the great unknown, has become for me an hypothesis, I mean a necessary dialectical tool.
[Coining phrase "null hypothesis"] In relation to any experiment we may speak of this hypothesis as the "null hypothesis," and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.
God is one among several hypotheses to account for the phenomena of human destiny, and it is now proving to be an inadequate hypothesis. To a great many people, including myself, this realization is a great relief, both intellectually and morally. It frees us to explore the real phenomena for which the God hypothesis seeks to account, to define them more accurately, and to work for a more satisfying set of concepts.
If we consistently act on the optimistic hypothesis, this hypothesis will tend to be realised; whilst by acting on the pessimistic hypothesis we can keep ourselves for ever in the pit of want.
Keynes was a great economist. In every discipline, progress comes from people who make hypotheses, most of which turn out to be wrong, but all of which ultimately point to the right answer. Now Keynes, in 'The General Theory of Employment, Interest and Money,' set forth a hypothesis which was a beautiful one, and it really altered the shape of economics. But it turned out that it was a wrong hypothesis. That doesn't mean that he wasn't a great man!
There is no logical impossibility in the hypothesis that the world sprang into being five minutes ago, exactly as it then was, with a population that "remembered" a wholly unreal past. There is no logically necessary connection between events at different times; therefore nothing that is happening now or will happen in the future can disprove the hypothesis that the world began five minutes ago.
There is no justifiable prediction about how the hypothesis will hold up in the future; its degree of corroboration simply is a historical statement describing how severely the hypothesis has been tested in the past.
It appears, then, to be a condition of a genuinely scientific hypothesis, that it be not destined always to remain an hypothesis, but be certain to be either proved or disproved by.. .comparison with observed facts.
However the machine would permit us to test the hypothesis for any special value of n. We could carry out such tests for a sequence of consecutive values n=2,3,.. up to, say, n=100. If the result of at least one test were negative, the hypothesis would prove to be false; otherwise our confidence in the hypothesis would increase, and we should feel encouraged to attempt establishing the hypothesis, instead of trying to construct a counterexample.
This hypothesis (Parallel hypothesis) would not destroy itself at all easily.
Mr. Darwin's hypothesis is not, so far as I am aware, inconsistent with any known biological fact; on the contrary, if admitted, the facts of Development, of Comparative Anatomy, of Geographical Distribution, and of Palaeontology, become connected together, and exhibit a meaning such as they never possessed before; and I, for one, am fully convinced that if not precisely true, that hypothesis is as near an approximation to the truth as, for example, the Copernican hypothesis was to the true theory of the planetary motions.
The first objection to Darwinism is that it is only a guess and was never anything more. It is called a "hypothesis," but the word "hypothesis," though euphonious, dignified and high-sounding, is merely a scientific synonym for the old-fashioned word "guess." If Darwin had advanced his views as a guess they would not have survived for a year, but they have floated for half a century, buoyed up by the inflated word "hypothesis." When it is understood that "hypothesis" means "guess," people will inspect it more carefully before accepting it.
But I should be very sorry if an interpretation founded on a most conjectural scientific hypothesis were to get fastened to the text in Genesis... The rate of change of scientific hypothesis is naturally much more rapid than that of Biblical interpretations, so that if an interpretation is founded on such an hypothesis, it may help to keep the hypothesis above ground long after it ought to be buried and forgotten.
This, it may be said, is no more than a hypothesis, but it satisfies the conditions of a legitimate hypothesis, by postulating the operation of no unknown or uncertain cause, but only of that force of precedent which in all times has been so strong to keep alive religious forms of which the original meaning is lost.
The hypothesis of molecular vortices is defined to be that which assumes - that each atom of matter consists of a nucleus or central point enveloped by an elastic atmosphere, which is retained in its position by attractive forces, and that the elasticity due to heat arises from the centrifugal force of those atmospheres revolving or oscillating about their nuclei or central points.According to this hypothesis, quantity of heat is the vis viva of the molecular revolutions or oscillations.
The scientific discovery appears first as the hypothesis of an analogy; and science tends to become independent of the hypothesis.
The hypothesis of matter's being at first evenly spread through the heavens is, in my opinion, inconsistent with the hypothesis of innate gravity without a supernatural power to reconcile them, and therefore, it infers a deity.
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