A Quote by Randy Schekman

I was driven completely by a desire to understand how cells worked. — © Randy Schekman
I was driven completely by a desire to understand how cells worked.
Once the principle is there, that cells have the same genes, my own personal belief is that we will, in the end, understand everything about how cells actually work.
Trying to understand fundamental processes that take place as organisms develop and how their various cells interact with one another - one can see what happens with those cells by asking questions about the fundamentals of biology.
I believe that we are a story-driven species and that we understand how things are put together, in the context of narrative. It's a shame that science hasn't been taught that way, in a long time. It's usually the fact completely devoid of any human experience or any idea of how the scientist came to that conclusion.
I've always thought of the project as a sort of sexually driven digestive system, that it was a consumer and a producer of matter. And it is desire driven, rather than driven by hunger or anything like that.
I am driven by a desire to see poverty end and economic security be a guaranteed capacity for every person. Most of the impediments or solutions are state-driven, not federally driven.
The task of neural science is to explain behaviour in terms of the activities of the brain. How does the brain marshall its millions of individual nerve cells to produce behaviour, and how are these cells influenced by the environment...? The last frontier of the biological sciences – their ultimate challenge – is to understand the biological basis of consciousness and the mental processes by which we perceive, act, learn, and remember.
The average person doesn't understand what a stem cell is. There's a lack of health literacy in our nation. So the public can't really get into this dialogue because they don't understand the complexity of stem cells, not the faith-based approach, not the ideological or political, but the science behind stem cells.
At the beginning of my career, my desire to understand was associated with a profound desire to act, with the wish to influence opinion and policy; but, over the years, this motivation has come to be of secondary importance, far behind my desire to understand.
I would argue that if you understand how the cells of the brain are organized into circuits, almost computational circuits if you will, and we see how information flows through those circuits and how it's transformed, we might have a much firmer grasp on why our brains make decisions the way that they do. If we get a handle on that, maybe we can overcome some of our limitations and at the very least we'll understand why we do what we do.
We're scientists; we're curious about how nature works, but we're also do-gooders. It's fantastic to think that the same experiments we'd do to understand how information gets into cells could have a practical side to them, too.
Conversational intelligence is hard-wired into every single human-being's cells. It's the way the cells engage with each other. Believe it or not, cells talk to each other. The immune system talks to the cells.
Most of our brain cells are glial cells, once thought to be mere support cells, but now understood as having a critical role in brain function. Glial cells in the human brain are markedly different from glial cells in other brains, suggesting that they may be important in the evolution of brain function.
One of the first papers I wrote at the University of Wisconsin, in 1977, was on stem cells. I realized that if I changed the environment that these cells were in, I could turn the cells into bone, and if I changed the environment a bit more, they would form fat cells.
...and suddenly it hits you: Human skin is actually made up of billions of tiny units of protoplasm, called "cells"! And what is even more interesting, the ones on the outside are all dying! This is a fact. Your skin is like an aggressive modern corporation, where the older veteran cells, who have finally worked their way to the top and obtained offices with nice views,are constantly being shoved out the window head first, without so much as a pension plan,by younger hotshot cells moving up from below.
Artists are people driven by the tension between the desire to communicate and the desire to hide.
In my lab, we are always thinking about how cells, bacterial cells, can talk to each other and then organize themselves into enormous groups that function in unison.
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