A Quote by Ryoji Noyori
Chiral receptor sites in the human body interact only with drug molecules having the proper absolute configuration, resulting in marked differences in the pharmacological activities of enantiomers.
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I can't get any satiation. My brain is wired in such a way that I - in my research, I probably have a lack of D1 and D2 receptor sites. These are dopamine receptor sites, and satiation is a process that involves a cascade.
Every thought, feeling, and emotion creates a molecule known as a neuropeptide. Neuropeptides travel throughout your body and hook onto receptor sites of cells and neurons. Your brain takes in the information, converts it into chemicals, and lets your whole body know if there's trouble in the world or cause for celebration. Your body is directly influenced as these molecules course through the bloodstream, delivering the energetic effect of whatever your brain is thinking and feeling.
Receptor chemistry, the chemistry of artificial receptor molecules, may be considered a generalized coordination chemistry, not limited to transition metal ions but extending to all types of substrates: cationic, anionic or neutral species of organic, inorganic or biological nature.
Suppose that you could mark the molecules in a glass of water; then pour the contents of the glass into the ocean and stir the latter throughly so as to distribute the marked molecules uniformly throughout the seven seas; if then you took a glass of water anywhere out of the ocean, you would find in it about a hundred of your marked molecules.
Many objects of our three-dimensional perceptual world are not only chiral but appear in nature in two versions, related at least ideally, as a chiral object and its mirror image.
The prevailing tendency to regard all the marked distinctions of human character as innate, and in the main indelible, and to ignore the irresistible proofs that by far the greater part of those differences, whether between individuals, races, or sexes are such as not only might but naturally would be produced by differences in circumstances, is one of the chief hinderances to the rational treatment of great social questions, and one of the greatest stumbling blocks to human improvement.
Why are atoms so small? ... Many examples have been devised to bring this fact home to an audience, none of them more impressive than the one used by Lord Kelvin: Suppose that you could mark the molecules in a glass of water, then pour the contents of the glass into the ocean and stir the latter thoroughly so as to distribute the marked molecules uniformly throughout the seven seas; if you then took a glass of water anywhere out of the ocean, you would find in it about a hundred of your marked molecules.
Every effective drug provokes in the human body a sort of disease of its own, and the stronger the drug, the more characteristic, and the more marked and more violent the disease. We should imitate nature, which sometimes cures a chronic affliction with another supervening disease, and prescribe for the illness we wish to cure, especially if chronic, a drug with power to provoke another, artificial disease, as similar as possible, and the former disease will be cured: fight like with like.
If you are having the experience of anxiety, your body is making adrenaline and cortisone, if you are having the experience of tranquility, your body starts making valium, if you are having the experience of exhilaration and joy, your body makes interleukins and interferons which are powerful anti-cancer drugs. So, your body is constantly converting your experiences into molecules.
The molecules that comprise our body are traceable to the crucibles of the centers of stars.These atoms and molecules are in us because, in fact, the universe is in us. And, we are not only figuratively, but literally, stardust.
You get to a point where it gets very complex, where you have money laundering activities, drug related activities, and terrorist support activities converging at certain points and becoming one.
Is it not possible to look beyond the canes, the wheelchairs, the braces, and the crutches into the hearts of the people who have need of these aids? They are human beings and want only to be treated as ordinary people. They may appear different, move awkwardly, and speak haltingly, but they have the same feelings. ... They want to be loved for what they are inside, without any prejudice for their impairment. Can there not be more tolerance for differences-differences in capacity, differences in body and in mind?
In all of my universe I have seen no law of nature, unchanging and inexorable. This universe presents only changing relationships which are sometimes seen as laws by short-lived awareness. These fleshy sensoria which we call self are ephemera withering in the blaze of infinity, fleeting aware of temporary conditions which confine our activities and change as our activities change. If you must label the absolute, use its proper name: Temporary.
In order for life to have appeared spontaneously on Earth, there first had to be hundreds of millions of protein molecules of the Ninth Configuration. But, given the size of the planet Earth, do you know how long it would take for just one of these protein molecules to appear by chance? Roughly 10 to the 243rd power, billions of years; and I find that far, far more fantastic than simply believing in a god.
We have had philosophies, we have ideologies, we have so many kinds of enterprises but despite that there are so many differences and the differences are having larger and larger gaps. If it is the truth, it has to be the truth for everyone. Everyone has to say: "This is The Truth". But it has to be the Absolute Truth. If it is not the Absolute Truth than what we believe into is not the reality. And this is the main reason why everything in the name of God, Divinity, everything has failed so far because it is not substantiated by reality.
The human body is constantly undergoing a process of decay and of reconstruction. First builded into the astral form in the womb of the mother, it is built up continually by the insetting of fresh materials. With every moment tiny molecules are passing away from it; with every moment tiny molecules are streaming into it.
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