A Quote by Stanley B. Prusiner

In science, each new result, sometimes quite surprising, heralds a step forward and allows one to discard some hypotheses, even though one or two of these might have been highly favored.
Certainly it is permitted to anyone to put forward whatever hypotheses he wishes, and to develop the logical consequences contained in those hypotheses. But in order that this work merit the name of Geometry, it is necessary that these hypotheses or postulates express the result of the more simple and elementary observations of physical figures.
Anything that promotes a kernel of science, even though it's exaggerated and hyped by Hollywood, I think is a step forward. We in the ivory tower ultimately have to realize that in some sense we have to sing for our supper.
Extraordinary individuals take one step back and two steps forward with most every challenge-and sometimes two steps back to one step forward. They harvest useful lessons and knowledge from what doesn't work, and they display a remarkable resiliency; and ability to bounce back from adversity.
True science is never speculative; it employs hypotheses as suggesting points for inquiry, but it never adopts the hypotheses as though they were demonstrated propositions.
So don't stop moving forward. For a while, you may feel as though you're taking two steps forward, one step back. And there may be some personal heartache along the way. But when you look your little ones in the eye, you will find your voice and take a stand for them. We are their voices. And we must have the courage to stand up for them, whatever the odds or however powerful the opposition might be.
The first step to living the life you want is leaving the life you don't want. Taking that first step forward is always the hardest. But then each step forward gets easier and easier. And each step forward gets you closer and closer. Until eventually, what had once been invisible, starts to be visible. And what had once felt impossible, starts to feel possible.
Any one who has studied the history of science knows that almost every great step therein has been made by the "anticipation of Nature," that is, by the invention of hypotheses, which, though verifiable, often had very little foundation to start with; and, not unfrequently, in spite of a long career of usefulness, turned out to be wholly erroneous in the long run.
Science walks forward on two feet, namely theory and experiment. Sometimes it is one foot which is put forward first, sometimes the other, but continuous progress is only made by the use of both.
Each step in life has been another step in an area that was a challenge, that is highly satisfying and that gives you a great sense of pride afterwards.
Every work of science great enough to be well remembered for a few generations affords some exemplification of the defective state of the art of reasoning of the time when it was written; and each chief step in science has been a lesson in logic.
The verb 'highly favored' (Luke 1:28) is the same as 'made us accepted' in Ephesians 1:6, referring to all of God's children. All true believers have been 'highly graced' by the Lord.
The fact that Science walks forward on two feet, namely theory and experiment, is nowhere better illustrated than in the two fields for slight contributions to which you have done me the great honour of awarding the the Nobel Prize in Physics for the year 1923. Sometimes it is one foot that is put forward first, sometimes the other, but continuous progress is only made by the use of both-by theorizing and then testing, or by finding new relations in the process of experimenting and then bringing the theoretical foot up and pushing it on beyond, and so on in unending alterations.
Most important of all, to be successful in life demands that a man make a personal commitment to excellence and to victory, even though the ultimate victory can never be completely won. Yet that victory might be pursued and wooed with every fiber of our body, with every bit of our might and all our effort. And each week, there is a new encounter; each day, there is a new challenge.
There have been repeated cases when nuclear war came ominously close, often a result of malfunctioning of early-warning systems and other accidents, sometimes [as a result of] highly adventurist acts of political leaders.
Sometimes two people need to step apart and make a space between that each might see the other anew, in a glance across a room or silhouetted against the moon.
If anyone offers conjectures about the truth of things from the mere possibility of hypotheses, I do not see by what stipulation anything certain can be determined in any science, since one or another set of hypotheses may always be devised which will appear to supply new difficulties.
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