A Quote by William John Macquorn Rankine

In thermodynamics as well as in other branches of molecular physics , the laws of phenomena have to a certain extent been anticipated, and their investigation facilitated, by the aid of hypotheses as to occult molecular structures and motions with which such phenomena are assumed to be connected. The hypothesis which has answered that purpose in the case of thermodynamics, is called that of "molecular vortices," or otherwise, the "centrifugal theory of elasticity.
It is possible to express the laws of thermodynamics in the form of independent principles , deduced by induction from the facts of observation and experiment, without reference to any hypothesis as to the occult molecular operations with which the sensible phenomena may be conceived to be connected; and that course will be followed in the body of the present treatise. But, in giving a brief historical sketch of the progress of thermodynamics, the progress of the hypothesis of thermic molecular motions cannot be wholly separated from that of the purely inductive theory.
The hypothesis of molecular vortices is defined to be that which assumes - that each atom of matter consists of a nucleus or central point enveloped by an elastic atmosphere, which is retained in its position by attractive forces, and that the elasticity due to heat arises from the centrifugal force of those atmospheres revolving or oscillating about their nuclei or central points.According to this hypothesis, quantity of heat is the vis viva of the molecular revolutions or oscillations.
We define thermodynamics ... as the investigation of the dynamical and thermal properties of bodies, deduced entirely from the first and second law of thermodynamics, without speculation as to the molecular constitution.
I have not been able to discover the cause of those properties of gravity from phenomena, and I frame no hypotheses; for whatever is not deduced from the phenomena is to be called a hypothesis, and hypotheses, whether metaphysical or physical, whether of occult qualities or mechanical, have no place in experimental philosophy.
The laws of thermodynamics may be regarded as particular cases of more general laws, applicable to all such states of matter as constitute Energy , or the capacity to perform work, which more general laws form the basis of the science of energetics, a science comprehending, as special branches, the theories of motion, heat, light , electricity , and all other physical phenomena.
The hypotheses which we accept ought to explain phenomena which we have observed. But they ought to do more than this; our hypotheses ought to foretell phenomena which have not yet been observed; ... because if the rule prevails, it includes all cases; and will determine them all, if we can only calculate its real consequences. Hence it will predict the results of new combinations, as well as explain the appearances which have occurred in old ones. And that it does this with certainty and correctness, is one mode in which the hypothesis is to be verified as right and useful.
Molecular chemistry, the chemistry of the covalent bond, is concerned with uncovering and mastering the rules that govern the structures, properties and transformations of molecular species.
Molecular evolution is not based on scientific authority. . . . There are assertions that such evolution occurred, but absolutely none are supported by pertinent experiments or calculations. Since no one knows molecular evolution by direct experience, and since there is no authority on which to base claims of knowledge, it can truly be said that . . . the assertion of Darwinian molecular evolution is merely bluster.
Molecular genetics can show off some surprising relationships like, for example, the close relationship of whales to hippopotamuses, which I think nobody ever guessed until molecular data was looked at. The closest relatives of whales are hippopotamuses, even closer than any other cloven-hoofed animals.
The whole edifice of modern physics is built up on the fundamental hypothesis of the atomic or molecular constitution of matter.
I am not a climatologist, but I don't think any of the other witnesses are either. I do work in the related field of atomic, molecular and optical physics. I have spent my professional life studying the interactions of visible and infrared radiation with gases - one of the main physical phenomena behind the greenhouse effect. I have published over 200 papers in peer reviewed scientific journals.
Evolution by natural selection is not an idle hypothesis. The genetic variation on which selection acts is well understood in principle all the way down to the molecular level.
The hypotheses we accept ought to explain phenomena which we have observed. But they ought to do more than this: our hypotheses ought to foretell phenomena which have not yet been observed.
Protein engineering is a technology of molecular machines - of molecular machines that are part of replicators - and so it comes from an area that already raises some of the issues that nanotechnology will raise.
In real science a hypothesis can never be proved true...A science which confines itself to correlating phenomena can never learn anything about the reality underlying the phenomena, while a science which goes further than this and introduces hypotheses about reality, can never acquire certain knowledge of a positive kind about reality; in whatever way we proceed, this is forever denied us.
It is a remarkable fact that the second law of thermodynamics has played in the history of science a fundamental role far beyond its original scope. Suffice it to mention Boltzmann's work on kinetic theory, Planck's discovery of quantum theory or Einstein's theory of spontaneous emission, which were all based on the second law of thermodynamics.
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