A Quote by Karl Barry Sharpless
The discipline, nonetheless, is exacting: everything that can be observed should be observed, even if it is only recalled as the bland background from which the intriguing bits pop out like Venus in the evening sky. The goal is always finding something new, hopefully unimagined and, better still, hitherto unimaginable.
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The goal of scientific physicians in their own science ... is to reduce the indeterminate. Statistics therefore apply only to cases in which the cause of the facts observed is still indeterminate.
We have repeatedly observed that while any whole is evolving, there is always going on an evolution of the parts into which it divides itself; but we have not observed that this equally holds of the totality of things, which is made up of parts within parts from the greatest down to the smallest.
I have observed private and proprietary colleges, like the University of Phoenix, and the market they serve. And I found it intriguing the way in which they are trying to deliver the product, with more accountability, for a price.
The hypotheses which we accept ought to explain phenomena which we have observed. But they ought to do more than this; our hypotheses ought to foretell phenomena which have not yet been observed; ... because if the rule prevails, it includes all cases; and will determine them all, if we can only calculate its real consequences. Hence it will predict the results of new combinations, as well as explain the appearances which have occurred in old ones. And that it does this with certainty and correctness, is one mode in which the hypothesis is to be verified as right and useful.
As a kid in Africa, you were so connected to nature itself because you went farming, watched the moon out at night, observed how the sky was different, and how the birds chanted different songs in the evening and the morning.
The orthodox school has witnessed for centuries that nature itself has never once cured any existing disease with another dissimilar one, however intense. What must we think of this school, which nevertheless has continued to treat chronic diseases allopathically, with medicines and formulas that can only cause a disease condition -God knows which -dissimilar to the one being treated? Even if these physicians have not hitherto observed nature attentively enough, the miserable results of their treatment should have taught them that they were on the wrong road.
No matter how many times something has been observed, it cannot be believed until it has been observed again.
The only marriage I've observed for any length of time is my parents - 35 years. I asked my pop, I go, 'Pop, 35 years - what do you hope for?' He's like, 'I hope you die first.'
A theoretical system does not merely state facts which have been observed and that logically deducible relations to other facts which have also been observed.
I have always observed that to succeed in the world one should appear like a fool but be wise.
What I've observed, and I think it's fair to give credit to the psychedelic experience for this, what I've observed is that nature builds on previously established levels of complexity.
I don't like talking about which bits I like or don't like about my body. Everybody has something they're not happy with, and my only advice would be, 'Do something about it - exercise or eat less, but don't do nothing!' Find ways to enhance the good bits and camouflage the bad bits.
Empirical laws [...] have only slight or even no value beyond the limits within which they have been observed to be true.
With a comedian, it's the opposite. You put that album out, and they've heard it. If they're coming out to see you, you'd better be doing new stuff. There's always a tiny part of the audience that want to hear certain bits of yours, or they've brought friends to see you, and they've told them about some of your bits. Then maybe you should do them.
The Heisenberg principle - If something is closely observed, the odds are it is going to be altered in the process. The more a price pattern is observed by speculators the more prone you have false signals; the more the market is a product of nonspeculative activity, the greater the significance of technical breakout
In a restaurant one is both observed and unobserved. Joy and sorrow can be displayed and observed "unwittingly," the writer scowling naively and the diners wondering, What the hell is he doing?
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