A Quote by Leroy Hood

In the late 1970s, when I was a professor at Caltech, I pioneered four instruments for analyzing genes and proteins that revolutionized modern biology - and one of these, the automated DNA sequencer, enabled the Human Genome Project.
A DNA sequence for the genome of bacteriophage ?X174 of approximately 5,375 nucleotides has been determined using the rapid and simple 'plus and minus' method. The sequence identifies many of the features responsible for the production of the proteins of the nine known genes of the organism, including initiation and termination sites for the proteins and RNAs. Two pairs of genes are coded by the same region of DNA using different reading frames.
Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to genes have bigger consequences: They can disable proteins and kill a creature.
About 1.2% of the human genome is made up of genes, things that encode for proteins, the stuff that we consider us. There is about 8.3% that's a virus. In other words we're probably about seven times more virus than we are human genes, which is kind of a weird way to thinking about yourself.
Recently, results of the Human Genome Project have shattered one of Science's fundamental core beliefs, the concept of genetic determinism. We have been led to believe that our genes determine the character of our lives, yet new research surprisingly reveals that it is the character of our lives that controls our genes. Rather than being victims of our heredity, we are actually masters of our genome.
We share half our genes with the banana. [After the announcement Jun 2000 that a working draft of the genetic sequence of humans had been completed by the Human Genome Project.]
Sometimes it is claimed by those who argue that race is just a social construct that the human genome project shows that because people share roughly 99% of their genes in common, that there are no races. This is silly.
During this period, I became interested in how the new techniques of cloning and sequencing DNA could influence the study of genetics and I was an early and active proponent of the Human Genome Sequencing Project.
Before the Human Genome Project, most scientists assumed, based on our complex brains and behaviors, that humans must have around 100,000 genes; some estimates went as high as 150,000.
By then, I was making the slow transition from classical biochemistry to molecular biology and becoming increasingly preoccupied with how genes act and how proteins are made.
During the decade following the discovery of the double-helical structure of DNA, the problem of translation - namely, how genetic information is used to synthesize proteins - was a central topic in molecular biology.
The involvement of clinicians, researchers, and, most importantly, the thousands of people who have donated DNA samples will help us to correlate genetic variation with individual variation in health and disease and help to deliver on the long-term promise of the Human Genome Project.
As was predicted at the beginning of the Human Genome Project, getting the sequence will be the easy part as only technical issues are involved. The hard part will be finding out what it means, because this poses intellectual problems of how to understand the participation of the genes in the functions of living cells.
And of course, identifying all human genes and proteins will have great medical significance.
Genes are biochemical recipes written in a four-letter alphabet called DNA.
If you know the mother's genome and the father's genome, and you see that the children have some genes that neither parent has, then you know that difference is either a mutation or a processing error.
Growing up in the Libya of the 1970s, I remember the prevalence of local bands who were as much influenced by Arabic musical traditions as by the Rolling Stones or the Beatles. But the project of 'Arabisation' soon got to them, too, and western musical instruments were declared forbidden as 'instruments of imperialism.'
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