A Quote by Siddhartha Mukherjee
Cell culture is a little like gardening. You sit and you look at cells, and then you see something and say, 'You know, that doesn't look right'.
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Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person. If telomeres are up for one cell type, they're up for others overall.
The number of cells in our bodies is defined by an equilibrium of opposing forces: mitosis adds cells, while programmed cell death removes them. Just as too much cell division can lead to a pathological increase in cell number, so can too little cell death.
You go to a restaurant with a friend for lunch and the next table, two people are sitting opposite each other. They don't talk! All they do is look at the screens of their cell phones and show it to the person that they're with. And when people do that to me, they want me to look at pictures on their cell phone? I can't even look at little things like that. I think it is all crazy.
Given the opportunity, under the right conditions, two cells from wildly different sources, a yeast cell, say, and a chicken erythrocyte, will touch, fuse, and the two nuclei will then fuse as well, and the new hybrid cell will now divide into monstrous progeny. Naked cells, lacking self-respect, do not seem to have any sense of self.
You know when you see a gorgeous boy on the street and you say to your friend, "Look at him!" and then your friend makes a face like, ugly? We all have such totally varied tastes that someone is going to look at you and think, yum-yum dee-lish, no matter what you think you look like. You just have to learn to see what they see.
If you say that you're all about a certain something, and look back and see that the choices that you've made don't reflect that, then there's something for you to look at.
I'm not perfect-looking and I don't say the right things, I'm a little different, nothing really special, but I guess I come across as a little more real to people and that comes through on the screen. I know I look young, but with the right make-up I can look older. I definitely feel older.
You can see the most beautiful things from the observation deck of the Empire State Building. I read somewhere that people on the street are supposed to look like ants, but that's not true. They look like little people. And the cars look like little cars. And even the buildings look little. It's like New York is a miniature replica of New York, which is nice, because you can see what it's really like, instead of how it feels when you're in the middle of it.
You don't really see a muscle as a part of you, in a way. You see it as a thing. You look at it as a thing and you say well this thing has to be built a little longer, the bicep has to be longer; or the tricep has to be thicker here in the elbow area. And you look at it and it doesn't even seem to belong to you. Like a sculpture. Then after looking at it a sculptor goes in with his thing and works a little bit, and you do maybe then some extra forced reps to get this lower part out. You form it. Just like a sculpture.
If stem cells divide equally, so both daughter cells look more or less the same, each one becomes another stem cell. If the split is unequal, neurons form prematurely.
It feels like now I - you know, I'm almost 80 years old - I can sit back and retire, you know, and say, 'Look, our young people are taking over.' And that's great. That's what I'd like to see.
I suppose I could understand it if men had simply forgotten unicorns, but not to see them at all, to look at them and see something else — what do they look to one another, then? What do trees look like to them, or houses, or real horses, or their own children?
I don't have time for their judgement and their stupidity and you know they lay down with their ugly wives in front of their ugly children and look at their loser lives and then they look at me and they say, 'I can't process it' well, no, you never will stop trying, just sit back and enjoy the show. You know?
When I'm unable to see a mistake I made right away. Maybe this is my Taurus mentality, but sometimes I don't see it and I don't see it and then, before you know it, I finally see it, and I'm like, "How the hell did I not see that? It was right in front of me all this time." And I have to look at the wake I left behind, the disappointment. That makes me feel weak.
Kevin Feige and I have very smart people who work for us, who make sure that we see everything. And that we actually see everything. They see everything, tell us about it, we see it. You have to have people who work with you, who say 'you have to look at this film'. And then you look at it. You really have to look at it. You have to look at movies all the time.
Look! You got sparklies like akri. He gives all of his to me. He say I look beautiful in sparklies, ‘specially them red ones that match my eyes. Here, Astrid. I know you can’t see it, Astrid, but it’s very lovely, like you. You need to wear that and then you have sparklies, too. But still no hornays. We need to fix you up with hornays one day so you can be a demon, too. It’s fun being a demon – except when people try to exercise you…Wait, that’s not the right word. I forget, but you know what I mean. (Simi)
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