A Quote by Elizabeth Blackburn

When you bring telomerase RNA levels down by using a mechanism that targets the RNA for destruction, the cells which were running on very high telomerase levels are now running on a lean diet of telomerase.
Cancer cells have had so many other things go wrong with them, genetic, non-genetic changes, that those cells, one of the things they then get selected for is that they have lots of telomerase because now the telomeres in those cells get maintained.
Ribosomes contain RNA, messenger RNA provides the information, transfer RNAs brings the amino acids; so the protein-making machinery is an RNA machinery, completely.
We think there are lifestyle factors that boost telomerase naturally.
I agree Maria Blasco has achieved amazing things with telomerase induction and we are hopeful this will translate to the human model.
For me, arguably the story of telomeres and telomerase began thousands of years ago, in the cornfields of the Maya highlands of Central America.
Our science and advisory board think that nuclear lamin dysfunction is a side-effect of DNA damage and mutations, rather than the cause. We are currently trying to mend nuclear dysfunction using Human Telomerase reverse transcriptase.
We believe that such a significant increase in longevity is due to the protective effect against cancer produced by caloric restriction - incidences fall by 40 percent if we compare them with the mice that produce more telomerase and have a normal diet - and, added to the presence of longer telomeres, this makes the mice live longer and better.
RNase H is a specific RNase that will cleave the RNA of a DNA/RNA duplex.
This enzyme, called telomerase, slows the rate at which telomeres degrade, and research indicates that healthy people with longer telomeres have less risk of developing the common illnesses of aging - like heart disease, diabetes, and cancer, which are three big killers today.
What I found out on Christmas Day 1984, through biochemical evidence, was that telomeres could be lengthened by the enzyme we called telomerase, which keeps the telomeres from wearing down. After I found that out, I went home and put on Bruce Springsteen's 'Born in the USA,' which was just out, and I danced and danced and danced.
Work by Maria Blasco, Calvin Harley, Michael Fossel, Woodring Wright and Shay and Ronald Depinho in particular are of interest but there are literally thousands of articles relating to telomerase, telomeres and the biology behind it.
We know that advanced economies with stable governments that borrow in their own currency are capable of running up very high levels of debt without crisis.
RNA interference has proven to be a quite reliable mechanism for turning genes off in a whole variety of different plants and animals.
You talk to any of the job creators, and they'll tell you one of the things that concerns them the most is the debt. And so high levels of indebtedness are going to lead to high levels of taxation, which lead to high level of unemployment.
It is a long time now since I started running but I still remember running up and down hills and running to school as a kid. When I was young I would run for fun and I didn't know back then that this would be my career.
While the olive is high in fat, it's monounsaturated fat, which, in a balanced diet, can help control heart disease by lowering cholesterol levels.
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