Top 15 Downers Quotes & Sayings

People who are poor, they suffer a lot. And people drink a lot and people take a lot of downers and there's a lot of unemployment.

I mean, for years [my father] would been doing everything imaginable ... from speed to downers to you name it. I used to call that "changing seats on the Titanic," and I used to say that I myself was not only changing seats on the Titanic but dating the crew.

This CD became something of a personal journey for me. The tone of the whole CD is uplifting and inspirational. It's an upper. We have enough downers in the world.

We had two bags of grass, seventy-five pellets of mescaline, five sheets of high powered blotter acid, a salt shaker half full of cocaine, and a whole galaxy of multi-colored uppers, downers, screamers, laughers... and also a quart of tequila, a quart of rum, a case of Budweiser, a pint of raw ether and two dozen amyls. Not that we needed all that for the trip, but once you get locked into a serious drug collection, the tendency is to push it as far as you can.

I loved downers, almost any kind. Loved the colors of them. Loved them yellow... I did. I would just have a bouquet in my hands at night.

You start doing the addictive behavior to feel good and then your receptors get overloaded with dopamine, then you stop doing the addictive thing and some of the receptors have shut down and you don't have enough dopamine to feel good. So then you feel bad and go back to the addictive behavior to get more dopamine. The strange thing is that it works with what we think of as uppers and downers and whatever you call gambling - sidewaysers.

For a wide-ranging look at literary matters, the 'Book Review Podcast' from the 'New York Times' is still one of the best. Presented by Pamela Paul, each episode has an interview with an author - recent guests have included Neil Gaiman and Sana Krasikov - plus a roundup of the uppers, downers and hanging-arounders on the U.S. bestsellers chart.

Sometimes, though, I feel that pushing books is a whole lot like pushing medicine. Think of books as pills. I have pills that cure ignorance and pills that cure boredom. I have pills to elevate moods and pills to open people's eyes to the awful truth: uppers and downers as they were. I sell pills to help people find themselves and pills to help them lose themselves when they require escape from the pressures and anxieties of life in a complex society.

The similarities between street drug abuse and psychotropic prescription drug use are disturbing. Both types are toxic. Both can cause psychosis, damage the brain and other organs, and even cause death. And neither type of mind-altering drugs, legal or illegal, treats disease. It's important to recognize that the only significant difference between many prescription psychotropic drugs and street drugs such as "speed" and "downers" is that prescription drugs are legal.

I started on the downers which were a hell of a lot better than the uppers because I was a nervous wreck.

As with real families, my fictional family on 'Life Goes On' had its ups and downs, and as part of the fictional downers, the actors were often called to cry on cue. This absolutely terrified me, because I was a pretty happy kid who didn't have much to cry about.

Put tattoos all up and down our thighs, do anything our parents would despise. Take uppers, downers, blues, and reds and yellows, our brains are turning into jello.

I always tell Phil we're like the party poopers. If we ever get invited to a player party, between the two of us, we're like the downers. Like, 'Put down that beer!' Or, 'Should you really be eating those nachos?'

Bookish people drolly claim to be addicted. I think, in some cases, this is literally true. . . . I suppose this makes me a small-time pusher, holding a couple of capsules of a novel compound, looking for vulnerable readers for whom it might turn out to be habit-forming. There's enough of them. When I walk into a bookshop--one of the big ones, a vast dispensary stacked with complex uppers and downers--I can't help thinking, my God, what army of junkies is all this feeding?

There's a big difference between somebody who does acid on weekends and somebody who takes downers every day.