Top 142 Genome Quotes & Sayings - Page 2

Simple genome engineering of bacteria and yeast is just the beginning of the rise of the true biohackers. This is a community of several thousand people, with skill sets ranging from self-taught software hackers to biology postdocs who are impatient with the structure of traditional institutional lab work.

Before the Human Genome Project, most scientists assumed, based on our complex brains and behaviors, that humans must have around 100,000 genes; some estimates went as high as 150,000.

Your genome sequence will become a vital part of your medical record, thereby providing critical information about how to optimize your wellness.

The genome was once thought to be just the blueprint for a living organism, like a combination of the architect's plan for a building and the builder's list of supplies. It specified the parts, the building blocks, and, somehow, the design of the whole, the way in which they are to be put together.

This is a whole new era where we're moving beyond little edits on single genes to being able to write whatever we want throughout the genome. The goal is to be able to change it as radically as our understanding permits.

Darwin talks about evolution, but he doesn't say how it started. Maybe the sense of mystery will dissolve in the face of science, but I am not so sure. We are all described by the human genome, but it's getting people nowhere.

People think genes are an absolute cause of traits. But the notion that the genome is the blueprint for humanity is a very bad metaphor. If you think we're hard-wired and deterministic, there should indeed be a lot more genes.

Human experience depends on everything that can influence states of the human brain, ranging from changes in our genome to changes in the global economy.

People think that Celera's trying to patent the whole human genome because it's been used as - I guess people in Washington learn how to do political attacks, and so it gets used as a political weapon, not as a factual one.

We have 200 trillion cells, and the outcome of each of them is almost 100 percent genetically determined. And that's what our experiment with the first synthetic genome proves, at least in the case of really simple bacteria. It's the interactions of all those separate genetic units that give us the physiology that we see.

If you're looking for your own idea of your own identity you know the human genome may not be the best place to look for it. You're just looking at a bunch of viruses.

During this period, I became interested in how the new techniques of cloning and sequencing DNA could influence the study of genetics and I was an early and active proponent of the Human Genome Sequencing Project.

I'm fascinated with genetic science, and I have been for a very long time. I always look at science and technology because I think that the developments in my lifetime have been so remarkable - and we're only at the tip of the iceberg with projects like decoding the human genome.

We live in a dancing matrix of viruses; they dart, rather like bees, from organism to organism, from plant to insect to mammal to me and back again, and into the sea, tugging along pieces of this genome, strings of genes from that, transplanting grafts of DNA, passing around heredity as though at a great party.

Although not yet routine, many cancer centers have the technology to sequence some or all of a patient's cancer genome. This can provide massive amounts of valuable information about your cancer, including whether you have genetic mutations and other abnormalities for which new drugs are available.

We are here to celebrate the completion of the first survey of the entire human genome. Without a doubt, this is the most important, most wondrous map ever produced by human kind.

A few dozen changes to the genome of a modern elephant - to give it subcutaneous fat, woolly hair and sebaceous glands - might suffice to create a variation that is functionally similar to the mammoth. Returning this keystone species to the tundras could stave off some effects of warming.

The human genome will not help us to understand the spiritual side of humankind, or to know who God is or what love is. The well-heeled couple who decide they want to use genetics to have a child that is a gifted musician may end up with a sullen adolescent who smokes marijuana and doesn't talk to them.

The ever quickening advances of science made possible by the success of the Human Genome Project will also soon let us see the essences of mental disease. Only after we understand them at the genetic level can we rationally seek out appropriate therapies for such illnesses as schizophrenia and bipolar disease.

Each part of our genome is unique. We would not be alive if there was not a single mathematical solution for our chromosomes. We would just be scrambled goo.

Cancer is a disease of the genome. And that's what happens. You make mistakes in a cell somewhere in your body that causes it to start to grow when it should've stopped, and that's cancer. And those mistakes are mistakes of DNA.

A lot of people think PMI is the genome project 2.0. No. This is about all the influences on disease - genetics is in there, but the environment is in there as well, health choices, behaviors, all the factors that are important, otherwise we're not doing what we promised we would do - which is in a holistic way look at how people stay healthy or how do they fall ill.

The day is not far off when we will be able to send a robotically controlled genome-sequencing unit in a probe to other planets to read the DNA sequence of any alien microbe life that may be there.

I think something very simple that everybody can do is they can participate in medical research as subjects. Personal genome project, for example, will take on as many subjects as we can find.

Plasticity is an intrinsic property of the human brain and represents evolution's invention to enable the nervous system to escape the restrictions of its own genome and thus adapt to environmental pressures, physiologic changes, and experiences.

Genomics is a new idea. Like the PC, it's not obvious at first that anyone would want one. It's like, 'Hey, we've already got one genome, why do we need more?'

While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require.

Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to genes have bigger consequences: They can disable proteins and kill a creature.

The virus that causes AIDS is the trickiest pathogen scientists have ever confronted. It mutates furiously, it has decoys to evade the immune system, it attacks the very cells that are trying to fight it, and it quickly hides itself in your genome.

Medicine will be personalized and preventive: Your genome might predict that you have an 80 percent chance of breast cancer by the time you are 50, but if you take a preventive drug starting when you are 40, the chance will drop to 2 percent.

While San Diego is continuing to produce world-class businesses that are changing lives with breakthroughs like mapping the human genome, we should also use innovation and technology to map a better future for our children.

We're collecting about 100,000 telomere lengths in saliva samples and then looking at how those relate to both the extensive longitudinal clinical records that Kaiser is collecting and the genome sequence variations.

People think if you have deciphered the genome of humans that you can change everything. But you cannot change everything, because you do not know what the genes mean, and you have no methods for changing them, and you can't do experiments with humans like you can with animals.

These days vampires gravitated toward particle accelerators, projects to decode the genome, and molecular biology. Once they had flocked to alchemy, anatomy, and electricity. If it went bang, involved blood, or promised to unlock the secrets of the universe, there was sure to be a vampire around.

Emotion is set in our genome and that we all have with a certain programmed nature that is modified by our experience so individually we have variations on the pattern. But in essence, your emotion of joy and mine are going to be extremely similar.

As was predicted at the beginning of the Human Genome Project, getting the sequence will be the easy part as only technical issues are involved. The hard part will be finding out what it means, because this poses intellectual problems of how to understand the participation of the genes in the functions of living cells.

An important finding is that by determining the genome sequences of an entire family, one can identify many DNA sequencing errors and thus greatly increase the accuracy of the data. This will ultimately help us understand the role of genetic variations in the diagnosis, treatment, and prevention of disease.

I'm looking for all the things that are beneficial in the human genome. Everything that I do is based on a very simple principle: things that are beneficial will spread through populations very quickly.

It will be the mother of all telescopes, and you can bet it will do for astronomy what genome sequencing is doing for biology. The clumsy, if utilitarian, name of this mirrored monster is Large Synoptic Survey Telescope, or LSST. You can't use it yet, but a peak in the Chilean Andes has been decapitated to provide a level spot for placement.

If you look on the fungal genome as being soldier candidates protecting the U.S. as our host defense, not only for the ecosystem but for our population... we should be saving our old-growth forests as a matter of national defense.

In 15 years, we've raised $225 million, sequenced the myeloma genome, and opened 45 trials of 23 drugs - six approved by the FDA - which have doubled the life span of multiple myeloma patients. I've taken both Velcade and Revlimid, which we helped develop.

My own diagnosis of my problem is a simpler one. It's that I share 50 per cent of my genome with a banana and 98 per cent with a chimpanzee. Banana's don't do psychological consistency. And the tiny part of us that's different - the special Homo sapiens bit - is faulty. It doesn't work. Sorry about that.

Evolution is all about passing on the genome to the next generation, adapting and surviving through generation after generation. From an evolutionary point of view, you and I are like the booster rockets designed to send the genetic payload into the next level of orbit and then drop off into the sea.

I thought we'd just sequence the genome once and that would be sufficient for most things in people's lifetimes. Now we're seeing how changeable and adaptable it is, which is why we're surviving and evolving as a species.

Sometimes it is claimed by those who argue that race is just a social construct that the human genome project shows that because people share roughly 99% of their genes in common, that there are no races. This is silly.

I would like to do a series about sequencing the human genome, and also analyze more human diversity among other ethnic groups - a 'Faces of America 2.'

Knowing what your parents have gives you hints of things, but your genome is a totally unique combination of and interchange of DNA from your parents. There is no one else like you genetically.

I respect and value the ideals of rugged individualism and self-reliance. But rugged individualism didn't defeat the British, it didn't get us to the moon, build our nation's highways, or map the human genome. We did that together. This is the high call of patriotism.

The involvement of clinicians, researchers, and, most importantly, the thousands of people who have donated DNA samples will help us to correlate genetic variation with individual variation in health and disease and help to deliver on the long-term promise of the Human Genome Project.

From the growth of the Internet through to the mapping of the human genome and our understanding of the human brain, the more we understand, the more there seems to be for us to explore.

Somewhere in our DNA must lie the key mutation (or, more probably, mutations) that set us apart—the mutations that make us the sort of creature that could wipe out its nearest relative, then dig up its bones and reassemble its genome.

It's terrifying the way molecular biology has become more and more jargon ridden. But I strongly believe that my book can be read by the intelligent layman. I want everyone who bought a copy of 'A Brief History of Time' to buy a copy of 'Genome'.

One of the most exciting aspects of 23andMe is that we're enabling you to watch a revolution unfold live during your lifetime, and I think that the decoding of the genome, in my opinion, is the most fascinating discovery of our lifetime, and you get to be part of it.

How did we cure polio, smallpox and send a man to the moon? How did we decode the human genome in just 13 years? Collaboration. Focus on a specific goal, and teamwork.

I have had my genome fully sequenced and have learned a great deal about which medications I would respond to and which might or would induce major side effects, along with knowing many medical conditions for which I'm particularly susceptible.

Some software is actually pretty good, by any standard. Think of the Mars Rovers, Google, and the Human Genome Project. Now, that's quality software!

Anybody that thought the genome was going to directly provide drugs was a fool. Biological networks are not simple, and making drugs to affect them won't be simple.

I think we're just scratching the surface. One of the most exciting aspects of 23andMe is that we're enabling you to watch a revolution unfold live during your lifetime, and I think that the decoding of the genome, in my opinion, is the most fascinating discovery of our lifetime, and you get to be part of it.

We can't any longer have the conventional understanding of genetics which everybody peddles because it is increasingly obvious that epigenetics - actually things which influence the genome's function - are much more important than we realised.

Understanding how Cas9 is able to locate specific 20-base-pair target sequences within genomes that are millions to billions of base pairs long may enable improvements to gene targeting and genome editing efforts in bacteria and other types of cells.