Significant anniversaries are solemnly commemorated - Japan's attack on the U.S. naval base at Pearl Harbor, for example.
If Donald Trump loses badly, it could mean the end of the GOP as one of the two significant parties.
Integrated is the expression of knowledge: an assembly is significant in Unity: united are their minds in the silent dynamism of all possibilities.
The [Edward] Snowden disclosures created this perception that people's privacy was being put at significant risk.
But most significant in this tidal wave of happiness was the surest fact of all: I was with Edward. Forever - Bella Cullen
The GOP can't even envision winning the White House if we lose a significant percentage of the Hispanic vote.
Close scrutiny of an object in nature will nearly always yield some significant fact.
If we were to impose greater sanctions on economic sectors, I think we could have a significant impact on Putin.
Every significant event that takes place in our lives is set to some kind of music.
It's important that I know what I'm doing before I assume responsibility over something as significant as the actors' guild.
The British government has learned that Saddam Hussein recently sought significant quantities of uranium from Africa.
The avian influenza found in mainland British Columbia poses no significant threat to human health.
Indeed, there's scarcely a week that goes by where I don't deal with a significant, often controversial national security issue.
In effect, there has been a significant shortfall in the overall amount of monetary policy stimulus since early 2009.
As with almost every significant aspect of the Bush presidency, its handling of 9/11 was a catastrophe from start to finish.
It is very significant that some of the most thoughtful and cultured men are partisans of a pure vegetable diet
Hamirpur along with the entire state has had witnessed significant development under the leadership of PK Dhumal.
Climate change is an issue I care passionately about and have dedicated a significant portion of my life to addressing.
The capacity to recognize significant factors in a given situation is limited by the context that arises from the level of consciousness of the observer.
Tax has generated a significant amount of discussion, and companies are forced to do what they can to maintain that global competitiveness and perform.
When you nurture people and add value to them without expecting anything in return, they feel significant.
A person who hasn't grieved a significant loss has unfinished business inside and can cause others great grief as a result.
I'm still alive to change the world and to do things that are significant. I don't know what they all may be, but I was put on this earth for a reason.
I believe that the federal government has significant constitutional powers, but I don't think it's effective to impose pipelines on communities.
The countenances of children, like those of animals, are masks, not faces, for they have not yet developed a significant profile of their own.
Washington, D.C., is the new Wall Street. No significant financial transaction of any consequence occurs without it.
There are still substantial areas of disagreement, .. you simply have to look at the public statements to see there is a significant gap.
We do not behave as if we believed that the affairs of our world were significant enough for the intervention of great men.
It's generally not wise to pick a fight with law enforcement in politics, especially when you're in the middle of a pretty significant scandal already.
The challenge of work-life balance is without question one of the most significant struggles faced by modern man.
No company that I ever hacked into reported any damages, which they were required to do for significant losses.
The economic importance of small businesses in Mississippi has always been significant, and it's well positioned to increase.
A good legible label is usually worth, for information, a ton of significant attitude and expression in a historical picture.
Young men do not usually become inactive in the Church because they are given too many significant things to do.
When we are not honest, we are cut off from a significant resource of ourselves, a vital dimension that is necessary for unity and wholeness.
It wasn't that he was specially ungenerous but that he put things off to give his generosity a longer and more significant route.
There is nothing in all the world more beautiful or significant of the laws of the universe than the nude human body.
Tax increases appear to have a very large sustained and highly significant negative impact on output.
To care for another person, in the most significant sense, is to help him grow and actualize himself.
I think that if you're doing something that's important, that's significant in your life, it takes some of the pain away.
New Zealand's taken some very significant decisions in relation to defence in the last two years.
We have cellphones and smartphones and iDevices and laptops and the ability to be perpetually connected. We never have to miss anything, significant or insignificant.
Having a better and more productive life than my monster father has been my most significant accomplishment.
The most significant event of the 20th century will be the fact that the North Americans speak English.
It's a normal thing for people to do, going on Facebook and seeing pictures of their exes with their new significant others.
We want everyone to prepare themselves for the reality that we are not going to be able to recover significant numbers of people.
The Apple Pie Hubbub was a significant novel for me, because that's when I first started using verbs.
We need to have a bigger and more significant role for national parliaments. There is not, in my view, a single European demos.
If there were a verb meaning "to believe falsely," it would not have any significant first person, present indicative.
The most significant and alarming consequence of early maturation is an increased risk for breast cancer in adulthood.
It is a significant gamble to assume that troops in our U.K. Armed Forces would volunteer for a Scottish Defence Force.
Run Adam will play a significant role in aspiring sportspersons' life to achieve their dreams.
Only black holes of very low mass would emit a significant amount of radiation.
One of the most significant characteristics of healthy self esteem is that it is the state of one who is not at war either with himself or with others.
Appearances are significant, and never more than in politics. You can always sway the crowd, provided you have a good story.
Values must be demonstrated through behaviors, but they are truly significant when they represent the beliefs of an entire organization.
The financial crisis involved significant failures in the functioning, regulation, and supervision of OTC derivatives markets.
If no one can do that, yeah, Donald Trump better man the lifeboats, because there's some significant chance he'll win the nomination.
I am a firm believer that you don't do anything significant by yourself. Again, maybe there are exceptions. There's the Picasso or the Mozart.
Revealing water in significant quantities on the Moon could truly be a turning point in space exploration.
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