A Quote by Mark McClellan
Pharmacogenomics holds great promise to shed scientific light on the often risky and costly process of drug development, and to provide greater confidence about the risks and benefits of drugs in specific populations. Pharmacogenomics is a new field, but we intend to do all we can to use it to promote the development of medicines. By providing practical guidance on how to turn the explosion of pharmacogenomic information into real evidence on new drugs, we are taking an important step toward that goal.
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We all want our drugs to be safe - and so an essential part of the pathway to the development of a new drug is approval by a regulator.
Various species of animals react differently to the same drug. Not only do the variations in the metabolism of a drug make it difficult to extrapolate results of animal experiments to man but they create a serious obstacle to the development of new therapeutic drugs.
In my opinion, in addition to the success we have achieved in launching new Vants and in pursuing development of a variety of drugs, one of our most important achievements has been the growth of Roivant itself as a platform to support the efficient identification and advancement of medicines across all of the companies in the Roivant family.
The cost of research, development and testing of a new drug is vastly greater than the cost of each dose produced. How should we pay for new medicines? Innovators should be rewarded according to the impact of their medicine, and people should contribute to these rewards according to their ability to pay.
An interesting thing about drugs is often, when a new drug is discovered, it takes a long time to figure out how do you do it.
I use drugs to work. I never use them to escape or for pleasure. When you turn to drugs, all you're doing is turning inside, anyway. I only use drugs for construction. It's like one of my architectural tools.
While American taxes pay for much of the research and development that goes into creating the new, life-saving drugs, American consumers continue to subsidize the cost of the drugs for consumers across the world.
The coaching process is unique in how it accomplishes leadership development. The coach works not by providing answers per se but by asking questions through which the leader gains new insights and takes new actions.
The similarities between street drug abuse and psychotropic prescription drug use are disturbing. Both types are toxic. Both can cause psychosis, damage the brain and other organs, and even cause death. And neither type of mind-altering drugs, legal or illegal, treats disease. It's important to recognize that the only significant difference between many prescription psychotropic drugs and street drugs such as "speed" and "downers" is that prescription drugs are legal.
Drugs are about dulling perception, about addiction and about behavioral repetition...What *psychedelics* are about is pattern- dissolving experiences of an extraordinarily high or different awareness. They are the exact opposite of drugs. They promote questioning , they promote consciousness, they promote value examinations, they promote the reconstruction of behavioral patterns.
When at the typewriter I am no longer where I site but am away across the mountains, in ancient cities or on the Great Plains among the buffalo. Often I think of what pitiful fools are those who use mind-altering drugs to seek feelings they do not have, each drug taking a little more from what they have of mind, leaving them a little less. Give the brain encouragement from study, from thinking, from visualizing, and no drugs are needed.
Drug use, some might say, is destroying this country. And we have laws against selling drugs, pushing drugs, using drugs, importing drugs. And the laws are good because we know what happens to people in societies and neighborhoods which become consumed by them. And so if people are violating the law by doing drugs, they ought to be accused and they ought to be
convicted and they ought to be sent up.
For all of life's discontents, according to the pharmaceutical industry, there is a drug and you should take it. Then for the side effects of that drug, then there's another drug, and so on. So we're all taking more drugs, and more expensive drugs.
Sociopaths are not inhibited by the notion that it's wrong to be addicted, or wrong to buy illegal drugs. Also, drinking or taking drugs can be a lot of fun, and even if it's not, it can dull that painful boredom for a while. So can certain other things, like taking risks, and particularly if you take a risk-averse person and you can manipulate him or her into taking risks, that's really fun.
I stopped taking drugs when I was 19, and who wants to drive a cab around New York with drugs in their car?
I don't find it easy dealing with people with drug problems. It helps if you're all taking drugs, all the same drugs.
